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...shape of the [[Dendrite#Dendritic_Arbor|dendritic arbor]]. Two main roles for starburst amacrine cell have been characterized. SACs are (1) important in
The asymmetric GABA connections are essential for the computation of direction selectivity. If you block the GABA channels in
28 KB (4,401 words) - 04:05, 20 July 2019
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...e side of the soma. Asymmetry of the dendritic arbor is an unusual feature for a [[Ganglion Cell|retinal ganglion cell]] because most of the dendrites of
...surround (and related asymmetric light response), the preferred direction for movement of a spot of light, and the space-time slant within the receptive
15 KB (2,410 words) - 04:08, 20 July 2019
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...., 2010). Retinal ganglion cells (RGCs) are the cells that are responsible for transferring information from the eye to the brain. These cells come in a r
...amed as such because there is not yet an accepted classification or scheme for the nomenclature of RGC subtypes. Studies conducted using W3 mice have been
8 KB (1,263 words) - 03:37, 24 June 2016
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...inhibition from the peripheral region of the receptive field is necessary for orientation selectivity<ref name="Bloomfield"></ref>
...oxin and strychnine on rabbit retinal ganglion cells: lateral interactions for cells with more complex receptive fields. J Physiol, 276: 277-298. http://j
16 KB (2,403 words) - 16:11, 17 November 2015
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...tion. The average diameter of [[Dendrite#Dentritic_Arbor|dendritic field]] for each type varies over 34 to 400 microns, and their overall shapes alone are
...l|bipolar cell]], and generally has a particular type of neurotransmitter. For example, one such population, AII, 'piggybacks' rod bipolar cells onto the
14 KB (2,076 words) - 04:05, 20 July 2019
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...Wire is based on the images that were acquired at the Max Planck Institute for Medical Research in Heidelberg, Germany. This dataset, known as E2198, was
...l|SAC]] dendrites with the opposite preferred direction, which is evidence for specificity of connections. In principle, a DSGC could indiscriminately rec
6 KB (998 words) - 18:26, 14 June 2016
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...As described above, there are four cell subtypes, each with own preference for direction. Each subtype of ON/OFF DSGCs has differences in dendritic patte
...rom SACs. The motion detection result is fed to higher parts of the brain for further processing.
9 KB (1,350 words) - 03:55, 20 July 2019
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Retinal ganglion cells (RGCs) are the cells that are responsible for transferring information from the eye to the brain. These cells come with d
...s at least) then passes information to the next relay station in the brain for sorting and integrating into further information processing channels.
11 KB (1,636 words) - 04:07, 20 July 2019
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...n a water trough which allows the sample to float in order to be collected for later microscopy.
The device was hand-cranked, and advanced a sample for cutting with a metal blade.<ref name="Hill_1770">Hill, John (1770). [http:/
3 KB (419 words) - 11:59, 2 September 2022
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...n. <i>j</i> is the index of the neuron when there is more than one neuron. For a linear neuron, the activation function is not present (or simply the iden
<em>C</em> is the correlation matrix for [[File:Hebb10.png]], provided that [[File:Hebb10.png]] has mean zero and va
3 KB (481 words) - 03:15, 24 June 2016
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...j</em> is the index of the neuron when there is more than one neuron. For a linear neuron, the activation function is not present (or simply the iden
...n, approximated by a Taylor series with terms of [[File:Oja2.png]] ignored for n>1 since η is small.
2 KB (242 words) - 03:23, 24 June 2016
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...n. <i>j</i> is the index of the neuron when there is more than one neuron. For a linear neuron, the activation function is not present (or simply the iden
...Rather than the entire set, there may only be ''subsets'' of the input set for which principal components analysis over each subset makes sense. This insi
3 KB (411 words) - 03:28, 24 June 2016
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...n. <i>j</i> is the index of the neuron when there is more than one neuron. For a linear neuron, the activation function is not present (or simply the iden
Substituting back into the equation for [[File:Sanger2.png]] and doing some rearrangement, we get:
5 KB (764 words) - 03:08, 24 June 2016
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...of the neuron when there is more than one neuron. The activation function for feedforward backpropagation is sigmoidal.]]
...on index and <em>j</em> being the output neuron index), then the equations for the network are as follows:
4 KB (665 words) - 03:14, 24 June 2016
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..., the lowest concentration of rods, and much smaller receptive field sizes for all cells.
...an focus better on faces and thus better read human emotions were selected for in breeding certain pet dog "species" and this is why they have "lost" the
3 KB (499 words) - 04:38, 20 July 2019
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...1987 by Luis B. Almeida<ref>Almeida, Luis B. (June 1987). "A learning rule for asynchronous perceptrons with feedback in a combinatorial environment." <em
...of the neuron when there is more than one neuron. The activation function for backpropagation is sigmoidal. [https://www.researchgate.net/figure/A-back-p
5 KB (751 words) - 02:44, 20 July 2019
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...of the neuron when there is more than one neuron. The activation function for backpropagation is sigmoidal.]]
...ets settle to some equilibrium state. Initially set [[File:CHL5.png]] to 0 for all non-input and non-output neurons.
7 KB (1,144 words) - 03:10, 24 June 2016
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...features of the input set which can then be used to reconstruct the input. For example, if the input consists of a 10x10 square array of binary pixels --
...ith neural networks"].<em>Science</em> <strong>313</strong>: 504-507</ref> For example, the set of 25-dimensional feature vectors in the example above mig
3 KB (465 words) - 03:02, 24 June 2016
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...n. <i>j</i> is the index of the neuron when there is more than one neuron. For the RBM, the activation function is logistic, and the activation is actuall
...) [http://lib.tkk.fi/Dipl/2011/urn100427.pdf "Improved Learning Algorithms for Restricted Boltzmann Machines"]. Aalto University.
3 KB (501 words) - 03:24, 24 June 2016
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...houghts are generated and where signals from the rest of the body are sent for processing. In order to understand the brain, we must go beyond the surface
...has been called the “final frontier,” the terminal goal in our search for universal knowledge. Yet we can more easily perceive the stars at the farth
7 KB (1,208 words) - 03:20, 24 June 2016
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...cent versions of [[Chrome]] and [[Firefox]]. Please follow the links above for help enabling WebGL on the browser of your choice.
845 B (132 words) - 04:55, 20 July 2019
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If WebGL is still not working for you with Firefox it's time to try [[Chrome]].
2 KB (385 words) - 04:54, 20 July 2019
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...ded was by using [[WebGL]] (Web Graphics Library). It is an HTML5 feature for rendering interactive 3D graphics without the use of plug-ins.
751 B (116 words) - 04:54, 20 July 2019
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Chrome is the preferred browser for EyeWire. WebGL is enabled by default in the latest version of Chrome. Updat
...lable. If possible, please ensure that you are running the latest drivers for your video card." That means that you'll have to configure your browser ma
2 KB (428 words) - 04:54, 20 July 2019
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You're done! Refer to the screenshots below for help on any of the steps.
...eans that you'll have to configure your browser manually to enable WebGL. For instructions move to the next section.
2 KB (295 words) - 04:55, 20 July 2019
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click a link that says ‘edit’ for that section. Click on this link. <br>
...e ‘MOSTEC Student Articles’ category. Click the edit link on the right for your page.<br>
1 KB (244 words) - 03:07, 24 June 2016
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...ould serve as targets for drugs...the idea of the connectome as the target for medications...” (Seung, 2012, 217)
...evolutionize the relatively archaic approach to mental disorders practiced for the most part today.
9 KB (1,338 words) - 05:38, 20 July 2019
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...all malfunction was very riveting. Therefore, I decided to make it my goal for the final essay to try and understand more about this type of condition.
...re a diverse number of different types of ion channels for each “ion.” For example, there are many different types of sodium ion channels that can var
16 KB (2,397 words) - 05:41, 20 July 2019
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Curiosity about the brain and memories has been present for centuries – many, including myself, have always been curious about how ou
...for the synapses to be strengthened there needs to be some sort of demand for those synapses. However, it is important to note that the weak synapses hav
9 KB (1,374 words) - 03:27, 24 June 2016
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...I was interested in this topic because I find the idea of freezing tissue for use later on fascinating. The possibilities that could sprout from successf
...ntation later on. At this point there is no way of saving harvested organs for extended periods of time, so if an appropriate donor is not immediately ava
10 KB (1,656 words) - 03:11, 24 June 2016
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...was currently known about the mechanisms underlying neuronal regeneration. For this paper, I found an article entitled ‘Etifoxine improves peripheral ne
...ingredient. Each group was then monitored over the course of several days for indications of nerve regeneration. They were subjected to tests to assess i
6 KB (964 words) - 04:55, 20 July 2019
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Kenneth Blum, Executive Director, Center for Brain Science, Harvard University
981 B (152 words) - 03:12, 24 June 2016
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...erature or pressure. However, often it is purely sporadic and can continue for long periods of time. Almost immediately after the loss of a limb, 90 to 98
...used by an injury to a peripheral nerve. At the time, the common treatment for causalgia was amputation, so he would observe his causalgia patients underg
9 KB (1,516 words) - 16:13, 30 July 2019
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...n of the variation in the complex human behavioral traits is not accounted for by the effects or genes of families. Therefore, what we do in life is not s
who had played their instruments for a mean period of 11.7 year
6 KB (1,004 words) - 03:19, 24 June 2016
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discusses causes of and treatments for, epilepsy, as well as their link to connectomics.
There are structural and genetic causes for epilepsy including Lissencephaly epilepsy, a structural cause, as well as i
8 KB (1,214 words) - 05:33, 20 July 2019
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...oblem by randomly creating new synapses to continually renew its potential for learning, while eliminating the synapses that aren’t useful” (Seung 90)
...eurons (Seung 88). Cell assemblies or synaptic chains can then be created for the strong synapse connections. This idea concerns the question of memory
9 KB (1,386 words) - 03:32, 24 June 2016
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.... We've also put up [[Starburst_Amacrine_Cell| starburst amacrine cells]] for some of our more advanced players.
...mistakes are caught, and allows us to award points. See the points section for more information on how points are awarded.
19 KB (3,313 words) - 05:21, 30 January 2019
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* [[Targeting the Connectome for Treatment of Mental Disorders]]
707 B (81 words) - 02:52, 24 June 2016
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For those interested in delving deeper into the science behind EyeWire. List of
...in2010COIN.pdf Machines that learn to segment images: a crucial technology for connectomics]
1 KB (195 words) - 05:45, 20 July 2019
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[[File:Eyewire_for_science.jpg|thumb|EyeWire: For Science! by Beth Almeida]]
...ages acquired using serial electron microscopy at the Max Planck Institute for Medical Research in Heidelberg, Germany. In order to accomplish this, we ha
6 KB (910 words) - 05:38, 30 January 2019
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...mples. It was created at the Max Planck Institute in Germany, specifically for the purpose of imaging neurons.<ref name="Denk">Denk W, Horstmann H (2004)
For a less technical explanation you can view the [http://blog.eyewire.org/behi
3 KB (484 words) - 18:23, 14 June 2016
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MOSTEC stands for the MIT Online Science, Technology, and Engineering Community. It is an ed
767 B (117 words) - 03:18, 24 June 2016
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...ground to play. EyeWire works best on high speed internet. It is optimized for use on Google Chrome.
*[[For parents]]
4 KB (477 words) - 20:16, 2 September 2015
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...time, e.g. overwearing of contact lenses, the body will try to compensate for this by growing blood vessels into the cornea. This can increase the chance
...met's membrane, and the corneal endothelium. The epithelium is responsible for protecting the rest of the cornea, as is Bowman's layer. The stroma makes u
21 KB (3,258 words) - 16:11, 17 November 2015
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...rch as a game that provides fun for the players and useful scientific data for the researchers.
...amount of data that is being generated by the neuroscience field. Eyewire, for instance, contributes by reconstructing neuronal volume data from electron
6 KB (768 words) - 18:43, 20 July 2019
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...wiam, michellewooten, Nseraf, nkem, ronin, and Dodam, we now have captions for the first tutorial video in French, Italian, Polish, Spanish, Greek, German
Would you like to submit captions for another language? E-mail us at [mailto:support@eyewire.org support@eyewire.
533 B (78 words) - 03:34, 24 June 2016
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...data the AI may “overlearn” it and not be able to generalize properly for new data sets. So the more training data we can feed into the AI, the bett
...learns how to piece together connected segments, the less effort there is for the human user.
3 KB (544 words) - 15:56, 17 November 2015
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...ero, which may explain the Reaper’s frigid personality and low tolerance for shenanigans and especially unwanted mergers.
The GrimReaper has little patience for rogue [[Mergers|mergers]] and seeks to eliminate them at any cost. Any mis
2 KB (362 words) - 21:44, 6 February 2019
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...f accuracy. Every branch is still traced by two different users to account for human error.
2 KB (361 words) - 04:49, 20 July 2019
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...g Eyewire '''every Friday from 10:00 PM to midnight Eastern'''. Enrollment for all of these events is automatic.
...tern'''. You receive bonuses based on how many cubes you trace. Enrollment for this event is automatic.
4 KB (696 words) - 17:19, 6 August 2019
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...nes your accuracy based on what was added and what was missed. The formula for the traditional F-score is:
...ion and recall. When a player does a cube there are four possible outcomes for every segment in that cube: a true positive result, a false positive result
3 KB (580 words) - 16:03, 17 November 2015
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...on the new amount of neural volume found. Players can also receive points for how much time they've spent on the cube.
...zing earns the player a bonus of 25 points for Level 1 cubes and 50 points for Level 2.
5 KB (893 words) - 16:02, 5 August 2019
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...exit the cube a player may ignore them and continue their trace as normal. For larger mergers and/or mergers the exit the cube, the player may leave out t
...les in EyeWire#Scythe | Scythe]], or [[Player_Roles#Administrators|Admin]] for help. If the AI merger exits the cube, a Scout, Scythe, or Admin should be
5 KB (828 words) - 03:27, 31 January 2019
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There are three ranks for regular players in the game. These are:
...f the player is close to the 90% threshold and has other desired qualities for scouting)
8 KB (1,200 words) - 02:50, 16 November 2019
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...e data, EyeWire accepts a sophisticated combination of the players' traces for each cube. This combination is called the consensus.
...y, the maximum weight a cube can reach is 4 before it becomes unassignable for enfranchised players.
4 KB (715 words) - 19:26, 13 August 2019
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...exit the cube a player may ignore them and continue their trace as normal. For larger mergers and/or mergers the exit the cube, the player may leave out t
For varying reasons the AI can create mergers. It can be because of a misalignm
5 KB (942 words) - 02:48, 16 November 2019
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...of the organelles, most of the proteins are synthesized in the cell body. For the purpose of [[Retinal Connectomics]], the cell body is generally uninfor
...I ([[Artificial Intelligence]]) has trouble with them, since it's designed for dendrites.
1 KB (227 words) - 15:59, 17 November 2015
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...h each other. Chemical synapses use neurotransmitters as a chemical signal for communicating information, while electrical synapses communicate informatio
...und in situations where it is necessary to synchronize electrical activity for many cells.<ref>Purves D, Augustine GJ, Fitzpatrick D, et al., editors. Neu
3 KB (464 words) - 16:11, 17 November 2015
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There are three ranks for players in the game. These are:
...only the promotions granted by HQ. To see what those are, the requirements for the promotions and the responsibilities of those ranks click here: [[Player
794 B (128 words) - 03:23, 24 June 2016
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...elves on creating a community environment that's appropriate and enjoyable for all ages. However, we know that as a parent, if your child plays EyeWire, y
====What standards do you have in the chat for child-friendly content? How are they enforced?====
7 KB (1,142 words) - 16:09, 20 July 2019
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A user who works for/with EyeWire HQ. Abilities include but are not limited to: editing cubes, m
...tionary#B|Branches]], for accuracy, or [[EyeWire_Dictionary#D|dendrites]], for simplicity.
10 KB (1,682 words) - 08:45, 23 October 2016
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...they offer huge point rewards. Be sure to get all the extensions and nubs for great accuracy as well.
...eins. They make up the micro-circulation of the body's circulatory system. For more [http://en.wikipedia.org/wiki/Capillary information].
2 KB (404 words) - 02:42, 16 November 2019
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...e. It is public and can be viewed by looking at a player's profile. Hints for improving accuracy can be found [http://blog.eyewire.org/tips-to-raise-your
...ing and editing cubes, moderating the chat and forum, presenting new cells for tracing and declaring cells complete, editing the blog and wiki, running in
37 KB (6,387 words) - 21:17, 13 March 2019
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...otoreceptor cells. Among their functions, horizontal cells are responsible for allowing eyes to adjust to see well under both bright and dim light conditi
One hypothesis [5][6] for facilitation by the horizontal cells proceeds as follows. Assume we have 10
7 KB (1,096 words) - 04:57, 4 September 2019
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We hope that this wiki will act as a useful resource for those conducting research in the retina and the rest of the visual system,
...dited a wiki before and require assistance, or if you have any suggestions for this wiki, [mailto:makasako@princeton.edu| email us] and we will be glad to
5 KB (703 words) - 18:25, 14 June 2016
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...els (irradiance) rather than image-related information, and are best known for their roles in synchronizing circadian rhythms with night and day, and ligh
2 KB (276 words) - 03:16, 24 June 2016
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...els (irradiance) rather than image-related information, and are best known for their roles in synchronizing circadian rhythms with night and day, and ligh
...sensitive retinal ganglion cells are the primary but not exclusive circuit for light aversion. Exp. Eye Res. 105, 60–69.
6 KB (963 words) - 03:18, 24 June 2016
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...S2 and S4. SAC in red, DRD4-RGCs in green. Right: DRD4-GFP retinas stained for GFP and vAChT. Scale= 100um. Image adapted from Huberman et al., 2009]]
...dorsal lateral geniculate nucleus (dLGN) and the superior colliculus (SC). For both areas, axon terminations are restricted to specific laminae. In the dL
8 KB (1,185 words) - 04:08, 20 July 2019
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...en P4-P10 mediate columnar specificity of CB2-RGCs, but are not imperative for laminar specificity (Huberman et al., 2008).
...led central projections for a RGC type with a complete mosaic to be mapped for the first time. This cell type was discovered by Huberman et al. in 2008.
8 KB (1,198 words) - 04:09, 20 July 2019
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...hough not all of them are selective. Both BC1s and BC2s are immunoreactive for [https://en.wikipedia.org/wiki/Tachykinin_receptor_3 Neurokinin-3 receptor]
3 KB (411 words) - 04:06, 20 July 2019
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...le = 100um. D. TRHR-GFP retina stained for GFP. E. TRHR-GFP retina stained for VAChT. F. Merge of GFP (green) and VAChT (green). Yellow arrow points to RG
...have been known since 1968, the central projections and molecular markers for each subtype of On-Off DSGC have not been fully uncovered. The use of trans
7 KB (1,016 words) - 03:36, 11 September 2019
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...accepts the consensus, a sophisticated combination of the players traces, for each cube.
*Often it is necessary for multiple Scythes to reap a cube in order to change the confidence of the se
2 KB (421 words) - 17:41, 17 November 2015
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...h each other. Chemical synapses use neurotransmitters as a chemical signal for communicating information, while electrical synapses communicate informatio
...und in situations where it is necessary to synchronize electrical activity for many cells.<ref>Purves D, Augustine GJ, Fitzpatrick D, et al., editors. Neu
3 KB (440 words) - 17:25, 17 November 2015
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...data the AI may “overlearn” it and not be able to generalize properly for new data sets. So the more training data we can feed into the AI, the bett
...learns how to piece together connected segments, the less effort there is for the human user.
3 KB (520 words) - 15:56, 17 November 2015
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...of the organelles, most of the proteins are synthesized in the cell body. For the purpose of [[Retinal Connectomics]], the cell body is generally uninfor
...I ([[Artificial Intelligence]]) has trouble with them, since it's designed for dendrites.
1 KB (219 words) - 16:00, 17 November 2015
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Chrome is the preferred browser for EyeWire. WebGL is enabled by default in the latest version of Chrome. Updat
...lable. If possible, please ensure that you are running the latest drivers for your video card." That means that you'll have to configure your browser ma
2 KB (388 words) - 18:32, 17 November 2015
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...rch as a game that provides fun for the players and useful scientific data for the researchers.
901 B (138 words) - 16:01, 17 November 2015
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...est average percentage correct is awarded the victory. Points are deducted for incorrectness.
...ccasionally, when it's a holiday, someone's birthday, or some other time for celebration, a spontaneous Happy Hour will be held with it's own rules.
4 KB (564 words) - 16:03, 17 November 2015
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If WebGL is still not working for you with Firefox it's time to try [[Chrome]].
2 KB (341 words) - 20:07, 17 November 2015
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Retinal ganglion cells (RGCs) are the cells that are responsible for transferring information from the eye to the brain. These cells come with d
...s at least) then passes information to the next relay station in the brain for sorting and integrating into further information processing channels.
10 KB (1,594 words) - 16:05, 17 November 2015
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...ero, which may explain the Reaper’s frigid personality and low tolerance for shenanigans and especially unwanted mergers.
The GrimReaper has little patience for rogue [[Mergers|mergers]] and seeks to eliminate them at any cost. Any mis
2 KB (337 words) - 16:16, 17 November 2015
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...exit the cube a player may ignore them and continue their trace as normal. For larger mergers and/or mergers the exit the cube, the player may leave out t
...e#Scouts| Scout]], [[Advanced Roles in EyeWire#Scythe | Scythe]], or Admin for help. If the AI merger exits the cube, a Scout, Scythe, or Admin should be
4 KB (777 words) - 16:50, 17 November 2015
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There are three ranks for regular players in the game. These are:
*Be a player for a long enough time and done enough cubes to have gathered the required expe
7 KB (1,106 words) - 21:36, 19 July 2019
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...nes your accuracy based on what was added and what was missed. The formula for the traditional F-score is:
...ion and recall. When a player does a cube there are four possible outcomes for every segment in that cube: a true positive result, a false positive result
3 KB (558 words) - 16:06, 17 November 2015
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...ded was by using [[WebGL]] (Web Graphics Library). It is an HTML5 feature for rendering interactive 3D graphics without the use of plug-ins.
659 B (104 words) - 16:07, 17 November 2015
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...e side of the soma. Asymmetry of the dendritic arbor is an unusual feature for a [[Ganglion Cell|retinal ganglion cell]] because most of the dendrites of
...surround (and related asymmetric light response), the preferred direction for movement of a spot of light, and the space-time slant within the receptive
15 KB (2,322 words) - 16:07, 17 November 2015
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...time, e.g. overwearing of contact lenses, the body will try to compensate for this by growing blood vessels into the cornea. This can increase the chance
...met's membrane, and the corneal endothelium. The epithelium is responsible for protecting the rest of the cornea, as is Bowman's layer. The stroma makes u
20 KB (3,160 words) - 16:11, 17 November 2015
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...As described above, there are four cell subtypes, each with own preference for direction. Each subtype of ON/OFF DSGCs has differences in dendritic patte
...rom SACs. The motion detection result is fed to higher parts of the brain for further processing.
9 KB (1,312 words) - 16:11, 17 November 2015
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...inhibition from the peripheral region of the receptive field is necessary for orientation selectivity<ref name="Bloomfield"></ref>
...oxin and strychnine on rabbit retinal ganglion cells: lateral interactions for cells with more complex receptive fields. J Physiol, 276: 277-298. http://j
16 KB (2,335 words) - 16:11, 17 November 2015
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[[File:Eyewire_for_science.jpg|thumb|EyeWire: For Science! by Beth Almeida]]
...ages acquired using serial electron microscopy at the Max Planck Institute for Medical Research in Heidelberg, Germany. In order to accomplish this, we ha
6 KB (867 words) - 16:21, 17 November 2015
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...exit the cube a player may ignore them and continue their trace as normal. For larger mergers and/or mergers the exit the cube, the player may leave out t
For varying reasons the AI can create mergers. It can be because of a misalignm
5 KB (895 words) - 16:13, 17 November 2015
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...tion. The average diameter of [[Dendrite#Dentritic_Arbor|dendritic field]] for each type varies over 34 to 400 microns, and their overall shapes alone are
...l|bipolar cell]], and generally has a particular type of neurotransmitter. For example, one such population, AII, 'piggybacks' rod bipolar cells onto the
14 KB (2,016 words) - 15:54, 17 November 2015
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...ers can also receive up to 20 points based on time spent on any given task for level 1 cells, or 40 points in a level 2 cell.
...reak in the 2D image. When faced with this challenge a player should look for clues like branch width and direction to help them figure out where the con
5 KB (834 words) - 15:50, 17 November 2015
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.... We've also put up [[Starburst_Amacrine_Cell| starburst amacrine cells]] for some of our more advanced players.
...mistakes are caught, and allows us to award points. See the points section for more information on how points are awarded.
17 KB (3,107 words) - 16:12, 17 November 2015
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...l|bipolar cell]], and generally has a particular type of neurotransmitter. For example, one such population, AII, 'piggybacks' rod bipolar cells onto the
Their overall shapes alone are enough to serve as criterion for the classification.
21 KB (898 words) - 16:16, 21 June 2016
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...C. et al. “Convolutional Networks Can Learn to Generate Affinity Graphs for Image Segmentation.” Neural Computation 22.2 (2011): 511-538. © 2009 Mas
4 KB (79 words) - 11:42, 15 June 2016
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3 KB (120 words) - 05:01, 8 July 2016
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19 KB (521 words) - 19:44, 30 December 2015
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...하이델베르크의 막스플랑크 의학연구소(Max Planck Institute for Medical Research)에서 연속 전자주사현미경(serial electron micros
8 KB (201 words) - 03:45, 8 January 2016
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...oxin and strychnine on rabbit retinal ganglion cells: lateral interactions for cells with more complex receptive fields. J Physiol, 276: 277-298. http://j
19 KB (538 words) - 16:12, 21 June 2016
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...dendrites, and the sparser processes below are [[Axon|axons]] (credit: MPI for Medical Research).]]
24 KB (979 words) - 09:53, 20 June 2016
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...T. It is public and can be viewed by looking at a player's profile. Hints for improving accuracy can be found here: http://blog.eyewire.org/tips-to-raise
...ing and editing cubes, moderating the chat and forum, presenting new cells for tracing and declaring cells complete, editing the blog and wiki, running in
34 KB (5,914 words) - 14:03, 14 June 2016
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...occur in an organism are dictated by the connections between the neurons. For more information read Dr. Seung's book "Connectome". You can see excerpts f
...volume many cubes with individual identification numbers are created, one for each of the different neurons passing through that volume or space in the d
39 KB (3,993 words) - 02:59, 15 March 2018
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...mples. It was created at the Max Planck Institute in Germany, specifically for the purpose of imaging neurons.<ref name="Denk">Denk W, Horstmann H (2004)
For a less technical explanation you can view the [http://blog.eyewire.org/behi
3 KB (466 words) - 18:23, 14 June 2016
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We hope that this wiki will act as a useful resource for those conducting research in the retina and the rest of the visual system,
...dited a wiki before and require assistance, or if you have any suggestions for this wiki, [mailto:makasako@princeton.edu| email us] and we will be glad to
4 KB (675 words) - 18:25, 14 June 2016
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...Wire is based on the images that were acquired at the Max Planck Institute for Medical Research in Heidelberg, Germany. This dataset, known as E2198, was
...l|SAC]] dendrites with the opposite preferred direction, which is evidence for specificity of connections. In principle, a DSGC could indiscriminately rec
6 KB (966 words) - 18:26, 14 June 2016
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...they offer huge point rewards. Be sure to get all the extensions and nubs for great accuracy as well.
...veins. They make up the microcirculation of the body's circulatory system. For more [http://en.wikipedia.org/wiki/Capillary information].
2 KB (376 words) - 18:27, 14 June 2016
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We hope that this wiki will act as a useful resource for those conducting research in the retina and the rest of the visual system,
...dited a wiki before and require assistance, or if you have any suggestions for this wiki, [mailto:makasako@princeton.edu| email us] and we will be glad to
4 KB (642 words) - 09:59, 20 June 2016
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...l|SAC]] dendrites with the opposite preferred direction, which is evidence for specificity of connections. In principle, a DSGC could indiscriminately rec
6 KB (951 words) - 01:27, 15 June 2016
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...ers can also receive up to 20 points based on time spent on any given task for level 1 cells, or 40 points in a level 2 cell.
...reak in the 2D image. When faced with this challenge a player should look for clues like branch width and direction to help them figure out where the con
5 KB (847 words) - 21:57, 19 August 2016
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*Meet all the requirements for being a scout
*Have been a scout for enough time (Usually this is in excess of one month)
7 KB (632 words) - 16:06, 27 September 2016
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...ero, which may explain the Reaper’s frigid personality and low tolerance for shenanigans and especially unwanted mergers.
The GrimReaper has little patience for rogue [[Mergers|mergers]] and seeks to eliminate them at any cost. Any mis
2 KB (331 words) - 15:26, 16 September 2016
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...accepts the consensus, a sophisticated combination of the players traces, for each cube.
*Often it is necessary for multiple Scythes to reap a cube in order to change the confidence of the se
3 KB (395 words) - 16:09, 16 September 2016
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...lable. If possible, please ensure that you are running the latest drivers for your video card." 那就说明你得按照上面的步骤手动设置游览
2 KB (260 words) - 16:42, 24 October 2016
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...at take longer. It should be noted that the number of points you can earn for time spent are limited. In other words don't just leave your browser open
...u feedback before you complete a task because we don’t know the answer. For accuracy it’s also important that we have several people independently co
17 KB (2,817 words) - 16:21, 12 November 2016
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...of the organelles, most of the proteins are synthesized in the cell body. For the purpose of [[Retinal Connectomics]], the cell body is generally uninfor
...I ([[Artificial Intelligence]]) has trouble with them, since it's designed for dendrites.
1 KB (219 words) - 18:32, 13 October 2016
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Retinal ganglion cells (RGCs) are the cells that are responsible for transferring information from the eye to the brain. These cells come with d
...s at least) then passes information to the next relay station in the brain for sorting and integrating into further information processing channels.
10 KB (1,589 words) - 16:03, 9 November 2016
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Retinal ganglion cells (RGCs) are the cells that are responsible for transferring information from the eye to the brain. These cells come with d
...s at least) then passes information to the next relay station in the brain for sorting and integrating into further information processing channels.
10 KB (1,589 words) - 16:05, 9 November 2016
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...of the organelles, most of the proteins are synthesized in the cell body. For the purpose of [[Retinal Connectomics]], the cell body is generally uninfor
...I ([[Artificial Intelligence]]) has trouble with them, since it's designed for dendrites.
1 KB (219 words) - 16:10, 9 November 2016
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...time, e.g. overwearing of contact lenses, the body will try to compensate for this by growing blood vessels into the cornea. This can increase the chance
...met's membrane, and the corneal endothelium. The epithelium is responsible for protecting the rest of the cornea, as is Bowman's layer. The stroma makes u
20 KB (3,160 words) - 16:14, 10 November 2016
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...any way, but if you want you can donate anything/something to crazyman4865 for all his hard work in creating this script.
<br>Available for scouts, scythes, mystics and admins. This can be found in the gear cog icon
11 KB (1,839 words) - 08:10, 29 January 2018
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...zfish, it is sometimes useful to know when you have an axon or a dendrite. For example, you may be wondering if a branch you've added belongs. If you coul
...re certainty, you'll want to go inside some cubes and look in the 2D panel for synapses along the borders of your neuron. When you've identified a synapse
4 KB (679 words) - 00:37, 12 March 2018
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...veins. They make up the microcirculation of the body's circulatory system. For more [http://en.wikipedia.org/wiki/Capillary information].
2 KB (419 words) - 17:17, 27 August 2019
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...C. et al. “Convolutional Networks Can Learn to Generate Affinity Graphs for Image Segmentation.” Neural Computation 22.2 (2011): 511-538. © 2009 Mas
4 KB (583 words) - 23:06, 19 July 2019
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...mples. It was created at the Max Planck Institute in Germany, specifically for the purpose of imaging neurons.<ref name="Denk">Denk W, Horstmann H (2004)
For a less technical explanation you can view the [http://blog.eyewire.org/behi
3 KB (485 words) - 23:13, 19 July 2019
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...l|bipolar cell]], and generally has a particular type of neurotransmitter. For example, one such population, AII, 'piggybacks' rod bipolar cells onto the
Amacrine cells are responsible for mediating "antagonistic inputs from bipolar cells in [a] ganglion cell's su
14 KB (1,950 words) - 04:31, 16 August 2019
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...overview to check it, scythe complete it, then return to submit it. Useful for finding little errors when a cell is nearing completion.
...arburst neurons reconstructed by eyewirers (starburst challenge) were used for a publication in nature: “Space–time wiring specificity supports direct
37 KB (6,363 words) - 01:42, 7 January 2020
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...015). The types of retinal ganglion cells: current status and implications for neuronal classification. Annu. Rev. Neurosci. 38, 221-246.
4 KB (692 words) - 03:52, 11 September 2019
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...le = 100um. D. TRHR-GFP retina stained for GFP. E. TRHR-GFP retina stained for VAChT. F. Merge of GFP (green) and VAChT (green). Yellow arrow points to RG
...have been known since 1968, the central projections and molecular markers for each subtype of On-Off DSGC have not been fully uncovered. The use of trans
7 KB (1,124 words) - 16:16, 21 September 2019
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...ls (less than 5% of cells of the inner nuclear layer). The specific reason for the existence of the two classes of horizontal cells is not yet known; it p
Amacrine cells appear to allow for ganglion cells to send temporally correlated signals to the brain: input to
19 KB (3,186 words) - 02:12, 18 January 2020
