Translations:Bipolar Cell/17/en

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The ON and OFF center circuits within the retina are a product of the either sign-conserving or sign-reversing synapse that the bipolar cell shares with its paired photoreceptor. Sign-conserving synapses result in an OFF center while sign-reversing synapses produce an ON center. The surround portion of the center/surround functionality is dependent upon the aggregate signals from surrounding horizontal and amacrine cells.