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...in whole mount CB2-GFP mouse retina. A. whole mount retina. Scale = 500um B. GFP positive cells. C. Alpha RGCs are immunpositive to SMI-32 cells. D. GF

The collicular termination of J-RGCs (of which JAM-B cells are a majority) is intriguing in light of a study in which Drager and

...when the light turned off. On the other hand, RGCs lacking evidence of JAM-B were nearly equally likely to be ON or OFF cells.

JAM-B cells respond selectively to upward motion. To test the direction sensitivi

JAM-B cells were first discovered by In-Jung Kim, Yifeng Zhang, Masahito Yamagata

The ON surround of a JAM-B cell is typically asymmetric, in that it is shifted in the direction of pre

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[[Image:jamb010_side.png|thumb|right|420px|A side view of a JAM-B cell showing the asymmetrical dendritic field.<ref name="kim2008" />]]

Junctional adhesion molecule B is a protein that in humans is encoded by the JAM2 gene. JAM2 has also been

...n protein 10 (CreER) under the control of regulatory elements from the JAM-B gene.

...ar the dorsal and ventral margins of the retina. Therefore, nearly all JAM-B cells in the nasal, central, and temporal regions of the retina are markedl

===Features of the JAM-B Receptive Field Shaping Direction Selectivity===

...f amacrine cells.<ref name="Cherry 2009">T. J. Cherry, J. M. Trimarchi, M. B. Stadler & C. L. Cepko (2009)[http://www.pnas.org/content/106/23/9495.full

...pect to that particular dendrite.<ref name="Denk 2002">Thomas Euler, Peter B. Detwiler & Winfried Denk (2002). [http://retina.anatomy.upenn.edu/pdfiles/

.... Even more notable is that the asymmetrical [[Dendrite|dendrites]] of JAM-B cells all point in the same direction, about 13 degrees nasal of ventral. R

...rgic amacrines. Indeed, the dendrites of both symmetric and asymmetric JAM-B cells are confined to the outer third of the inner plexiform layer.

[[Image:jamb010_side.png|thumb|right|420px|A side view of a JAM-B cell showing the asymmetrical dendritic field.<ref name="kim2008" />]] ...cell's dendritic arbor can be used to identify a cell. In about 85% of JAM-B cells, there exists a marked asymmetry in the dendritic arbor.<ref name="ki

...tein [https://en.wikipedia.org/wiki/JAM2 Junction Adhesion Molecule B (JAM-B)]. J-RGCs are direction selective OFF RGCs, responding specifically to upwa

...arbors. Colors correspond to orientation of preferred direction. Figure B shows a bottom view of the traced arbors.<ref name="briggman2011">K. L. Bri

...ction potentials. <ref name="Hodgkin">Hodgkin, A. L., Huxley, A. F., Katz, B., (1952) [http://jp.physoc.org/content/116/4/424.full.pdf Measurement of Cu