J-RGC

Introduction

A type of retinal ganglion cell found in mice, JAM-B cells are named after Junctional Adhesion Molecule B, the molecular marker first used to define them as a distinct subset of retinal ganglion cells. JAM-B share many traits in addition to the presence of this molecule. They are all OFF RGCs, with asymmetric dendritic arbors aligned in a dorsal-to-ventral direction across the retina (source: Kim et al.) They respond specifically to upward motion. Their deepest importance to the study and categorization of cells in the retina lies in that they were the first RGC to be classified using a molecular marker.