https://wiki.eyewire.org/index.php?title=index.php&&title=J-RGC&feed=atom&action=history
J-RGC - Revision history
2024-03-29T11:44:07Z
Revision history for this page on the wiki
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https://wiki.eyewire.org/index.php?title=J-RGC&diff=12456&oldid=prev
Hawaiisunfun at 04:08, 20 July 2019
2019-07-20T04:08:35Z
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Hawaiisunfun
https://wiki.eyewire.org/index.php?title=J-RGC&diff=8533&oldid=prev
Nkem test: Marked this version for translation
2015-11-17T16:07:45Z
<p>Marked this version for translation</p>
<a href="https://wiki.eyewire.org/index.php?title=J-RGC&diff=8533&oldid=8530">Show changes</a>
Nkem test
https://wiki.eyewire.org/index.php?title=J-RGC&diff=8530&oldid=prev
Nkem test at 16:07, 17 November 2015
2015-11-17T16:07:38Z
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Nkem test
https://wiki.eyewire.org/index.php?title=J-RGC&diff=6782&oldid=prev
Miopio at 18:57, 24 September 2015
2015-09-24T18:57:57Z
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<td colspan='2' style="background-color: white; color:black; text-align: center;">Revision as of 18:57, 24 September 2015</td>
</tr><tr><td colspan="2" class="diff-lineno" id="L1" >Line 1:</td>
<td colspan="2" class="diff-lineno">Line 1:</td></tr>
<tr><td class='diff-marker'> </td><td style="background-color: #f9f9f9; color: #333333; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #e6e6e6; vertical-align: top; white-space: pre-wrap;"><div>[[Image:jamb010_side.png|thumb|right|420px|A side view of a JAM-B cell showing the asymmetrical dendritic field.<ref name="kim2008" />]]</div></td><td class='diff-marker'> </td><td style="background-color: #f9f9f9; color: #333333; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #e6e6e6; vertical-align: top; white-space: pre-wrap;"><div>[[Image:jamb010_side.png|thumb|right|420px|A side view of a JAM-B cell showing the asymmetrical dendritic field.<ref name="kim2008" />]]</div></td></tr>
<tr><td class='diff-marker'> </td><td style="background-color: #f9f9f9; color: #333333; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #e6e6e6; vertical-align: top; white-space: pre-wrap;"></td><td class='diff-marker'> </td><td style="background-color: #f9f9f9; color: #333333; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #e6e6e6; vertical-align: top; white-space: pre-wrap;"></td></tr>
<tr><td class='diff-marker'>−</td><td style="color:black; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div>'''J-RGCs''' are retinal ganglion cells defined by their expression of the protein [https://en.wikipedia.org/wiki/JAM2 Junction Adhesion Molecule B (JAM-B)]. J-RGCs are direction selective OFF RGCs, responding specifically to upward motion in the visual field.<ref name="kim2008">In-Jung Kim et al. [http://hebb.mit.edu/courses/connectomics/Kim%20molecular%20identification%20retinal%20cell%20type%20upward%20motion%2008.pdf Molecular identification of a retinal cell type that responds to upward motion] (2008). Nature <strong>452</strong>: 478-482</ref> They can be recognized by their asymmetric [[Dendrite#Dendritic_Arbor|dendritic arbors]] aligned in a dorsal-to-ventral direction across the retina. Like many direction selective ganglion cells, they project heavily to the superior colliculus (SC), but also innervate the dorsal lateral geniculate nucleus (dLGN). This was the first cell type in the retina to be classified based on the presence of a molecular biomarker.</div></td><td class='diff-marker'>+</td><td style="color:black; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div>'''J-RGCs''' are retinal ganglion cells defined by their expression of the protein [https://en.wikipedia.org/wiki/JAM2 Junction Adhesion Molecule B (JAM-B)]. J-RGCs are direction selective OFF RGCs, responding specifically to upward motion in the visual field.<ref name="kim2008">In-Jung Kim et al. [http://hebb.mit.edu/courses/connectomics/Kim%20molecular%20identification%20retinal%20cell%20type%20upward%20motion%2008.pdf Molecular identification of a retinal cell type that responds to upward motion] (2008). Nature <strong>452</strong>: 478-482</ref> They can be recognized by their asymmetric [[Dendrite#Dendritic_Arbor|dendritic arbors]] aligned in a dorsal-to-ventral direction across the retina. Like many direction selective ganglion cells, they project heavily to the superior colliculus (SC), but also innervate the dorsal lateral geniculate nucleus (dLGN). This was the first cell type in the retina to be classified based on the presence of a molecular biomarker <ins class="diffchange diffchange-inline">(?check)</ins>.</div></td></tr>
<tr><td class='diff-marker'> </td><td style="background-color: #f9f9f9; color: #333333; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #e6e6e6; vertical-align: top; white-space: pre-wrap;"></td><td class='diff-marker'> </td><td style="background-color: #f9f9f9; color: #333333; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #e6e6e6; vertical-align: top; white-space: pre-wrap;"></td></tr>
<tr><td class='diff-marker'> </td><td style="background-color: #f9f9f9; color: #333333; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #e6e6e6; vertical-align: top; white-space: pre-wrap;"><div>== Anatomy ==</div></td><td class='diff-marker'> </td><td style="background-color: #f9f9f9; color: #333333; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #e6e6e6; vertical-align: top; white-space: pre-wrap;"><div>== Anatomy ==</div></td></tr>
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Miopio
https://wiki.eyewire.org/index.php?title=J-RGC&diff=6781&oldid=prev
Miopio at 18:57, 24 September 2015
2015-09-24T18:57:39Z
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<td colspan='2' style="background-color: white; color:black; text-align: center;">Revision as of 18:57, 24 September 2015</td>
</tr><tr><td colspan="2" class="diff-lineno" id="L1" >Line 1:</td>
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<tr><td class='diff-marker'> </td><td style="background-color: #f9f9f9; color: #333333; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #e6e6e6; vertical-align: top; white-space: pre-wrap;"><div>[[Image:jamb010_side.png|thumb|right|420px|A side view of a JAM-B cell showing the asymmetrical dendritic field.<ref name="kim2008" />]]</div></td><td class='diff-marker'> </td><td style="background-color: #f9f9f9; color: #333333; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #e6e6e6; vertical-align: top; white-space: pre-wrap;"><div>[[Image:jamb010_side.png|thumb|right|420px|A side view of a JAM-B cell showing the asymmetrical dendritic field.<ref name="kim2008" />]]</div></td></tr>
<tr><td class='diff-marker'> </td><td style="background-color: #f9f9f9; color: #333333; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #e6e6e6; vertical-align: top; white-space: pre-wrap;"></td><td class='diff-marker'> </td><td style="background-color: #f9f9f9; color: #333333; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #e6e6e6; vertical-align: top; white-space: pre-wrap;"></td></tr>
<tr><td class='diff-marker'>−</td><td style="color:black; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div>'''J-RGCs''' are retinal ganglion cells defined by their expression of the protein [https://en.wikipedia.org/wiki/JAM2 Junction Adhesion Molecule B (JAM-B)]. J-RGCs are OFF RGCs <del class="diffchange diffchange-inline">that are direction selective</del>, responding specifically to upward motion in the visual field.<ref name="kim2008">In-Jung Kim et al. [http://hebb.mit.edu/courses/connectomics/Kim%20molecular%20identification%20retinal%20cell%20type%20upward%20motion%2008.pdf Molecular identification of a retinal cell type that responds to upward motion] (2008). Nature <strong>452</strong>: 478-482</ref> They can be recognized by their asymmetric [[Dendrite#Dendritic_Arbor|dendritic arbors]] aligned in a dorsal-to-ventral direction across the retina. This was the first cell type in the retina to be classified based on the presence of a molecular biomarker.</div></td><td class='diff-marker'>+</td><td style="color:black; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div>'''J-RGCs''' are retinal ganglion cells defined by their expression of the protein [https://en.wikipedia.org/wiki/JAM2 Junction Adhesion Molecule B (JAM-B)]. J-RGCs are <ins class="diffchange diffchange-inline">direction selective </ins>OFF RGCs, responding specifically to upward motion in the visual field.<ref name="kim2008">In-Jung Kim et al. [http://hebb.mit.edu/courses/connectomics/Kim%20molecular%20identification%20retinal%20cell%20type%20upward%20motion%2008.pdf Molecular identification of a retinal cell type that responds to upward motion] (2008). Nature <strong>452</strong>: 478-482</ref> They can be recognized by their asymmetric [[Dendrite#Dendritic_Arbor|dendritic arbors]] aligned in a dorsal-to-ventral direction across the retina<ins class="diffchange diffchange-inline">. Like many direction selective ganglion cells, they project heavily to the superior colliculus (SC), but also innervate the dorsal lateral geniculate nucleus (dLGN)</ins>. This was the first cell type in the retina to be classified based on the presence of a molecular biomarker.</div></td></tr>
<tr><td class='diff-marker'> </td><td style="background-color: #f9f9f9; color: #333333; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #e6e6e6; vertical-align: top; white-space: pre-wrap;"></td><td class='diff-marker'> </td><td style="background-color: #f9f9f9; color: #333333; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #e6e6e6; vertical-align: top; white-space: pre-wrap;"></td></tr>
<tr><td class='diff-marker'> </td><td style="background-color: #f9f9f9; color: #333333; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #e6e6e6; vertical-align: top; white-space: pre-wrap;"><div>== Anatomy ==</div></td><td class='diff-marker'> </td><td style="background-color: #f9f9f9; color: #333333; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #e6e6e6; vertical-align: top; white-space: pre-wrap;"><div>== Anatomy ==</div></td></tr>
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Miopio
https://wiki.eyewire.org/index.php?title=J-RGC&diff=6774&oldid=prev
Miopio at 18:19, 24 September 2015
2015-09-24T18:19:35Z
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<td colspan='2' style="background-color: white; color:black; text-align: center;">Revision as of 18:19, 24 September 2015</td>
</tr><tr><td colspan="2" class="diff-lineno" id="L1" >Line 1:</td>
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<tr><td class='diff-marker'> </td><td style="background-color: #f9f9f9; color: #333333; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #e6e6e6; vertical-align: top; white-space: pre-wrap;"><div>[[Image:jamb010_side.png|thumb|right|420px|A side view of a JAM-B cell showing the asymmetrical dendritic field.<ref name="kim2008" />]]</div></td><td class='diff-marker'> </td><td style="background-color: #f9f9f9; color: #333333; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #e6e6e6; vertical-align: top; white-space: pre-wrap;"><div>[[Image:jamb010_side.png|thumb|right|420px|A side view of a JAM-B cell showing the asymmetrical dendritic field.<ref name="kim2008" />]]</div></td></tr>
<tr><td class='diff-marker'> </td><td style="background-color: #f9f9f9; color: #333333; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #e6e6e6; vertical-align: top; white-space: pre-wrap;"></td><td class='diff-marker'> </td><td style="background-color: #f9f9f9; color: #333333; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #e6e6e6; vertical-align: top; white-space: pre-wrap;"></td></tr>
<tr><td class='diff-marker'>−</td><td style="color:black; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div>'''J-RGCs''' are retinal ganglion cells defined by their expression of the protein [https://en.wikipedia.org/wiki/JAM2 Junction Adhesion Molecule B (JAM-B)]. J-RGCs are OFF RGCs that are direction selective, responding specifically to upward motion in the visual field.<ref name="kim2008">In-Jung Kim et al. [http://hebb.mit.edu/courses/connectomics/Kim%20molecular%20identification%20retinal%20cell%20type%20upward%20motion%2008.pdf Molecular identification of a retinal cell type that responds to upward motion] (2008). Nature <strong>452</strong>: 478-482</ref> <del class="diffchange diffchange-inline">J-RGCs </del>can be recognized by their asymmetric [[Dendrite#Dendritic_Arbor|dendritic arbors]] aligned in a dorsal-to-ventral direction across the retina. This was the first cell type in the retina to be classified based on the presence of a molecular biomarker.</div></td><td class='diff-marker'>+</td><td style="color:black; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div>'''J-RGCs''' are retinal ganglion cells defined by their expression of the protein [https://en.wikipedia.org/wiki/JAM2 Junction Adhesion Molecule B (JAM-B)]. J-RGCs are OFF RGCs that are direction selective, responding specifically to upward motion in the visual field.<ref name="kim2008">In-Jung Kim et al. [http://hebb.mit.edu/courses/connectomics/Kim%20molecular%20identification%20retinal%20cell%20type%20upward%20motion%2008.pdf Molecular identification of a retinal cell type that responds to upward motion] (2008). Nature <strong>452</strong>: 478-482</ref> <ins class="diffchange diffchange-inline">They </ins>can be recognized by their asymmetric [[Dendrite#Dendritic_Arbor|dendritic arbors]] aligned in a dorsal-to-ventral direction across the retina. This was the first cell type in the retina to be classified based on the presence of a molecular biomarker.</div></td></tr>
<tr><td class='diff-marker'> </td><td style="background-color: #f9f9f9; color: #333333; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #e6e6e6; vertical-align: top; white-space: pre-wrap;"></td><td class='diff-marker'> </td><td style="background-color: #f9f9f9; color: #333333; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #e6e6e6; vertical-align: top; white-space: pre-wrap;"></td></tr>
<tr><td class='diff-marker'> </td><td style="background-color: #f9f9f9; color: #333333; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #e6e6e6; vertical-align: top; white-space: pre-wrap;"><div>== Anatomy ==</div></td><td class='diff-marker'> </td><td style="background-color: #f9f9f9; color: #333333; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #e6e6e6; vertical-align: top; white-space: pre-wrap;"><div>== Anatomy ==</div></td></tr>
</table>
Miopio
https://wiki.eyewire.org/index.php?title=J-RGC&diff=6772&oldid=prev
Miopio at 17:42, 24 September 2015
2015-09-24T17:42:18Z
<p></p>
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<td colspan='2' style="background-color: white; color:black; text-align: center;">Revision as of 17:42, 24 September 2015</td>
</tr><tr><td colspan="2" class="diff-lineno" id="L1" >Line 1:</td>
<td colspan="2" class="diff-lineno">Line 1:</td></tr>
<tr><td class='diff-marker'> </td><td style="background-color: #f9f9f9; color: #333333; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #e6e6e6; vertical-align: top; white-space: pre-wrap;"><div>[[Image:jamb010_side.png|thumb|right|420px|A side view of a JAM-B cell showing the asymmetrical dendritic field.<ref name="kim2008" />]]</div></td><td class='diff-marker'> </td><td style="background-color: #f9f9f9; color: #333333; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #e6e6e6; vertical-align: top; white-space: pre-wrap;"><div>[[Image:jamb010_side.png|thumb|right|420px|A side view of a JAM-B cell showing the asymmetrical dendritic field.<ref name="kim2008" />]]</div></td></tr>
<tr><td class='diff-marker'> </td><td style="background-color: #f9f9f9; color: #333333; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #e6e6e6; vertical-align: top; white-space: pre-wrap;"></td><td class='diff-marker'> </td><td style="background-color: #f9f9f9; color: #333333; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #e6e6e6; vertical-align: top; white-space: pre-wrap;"></td></tr>
<tr><td class='diff-marker'>−</td><td style="color:black; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div>'''J-RGCs''' are retinal ganglion cells defined by their expression of the protein [https://en.wikipedia.org/wiki/JAM2 Junction Adhesion Molecule B (JAM-B)]. J-RGCs are OFF RGCs that are direction selective, responding specifically to upward motion in the visual field. <ref name="kim2008">In-Jung Kim et al. [http://hebb.mit.edu/courses/connectomics/Kim%20molecular%20identification%20retinal%20cell%20type%20upward%20motion%2008.pdf Molecular identification of a retinal cell type that responds to upward motion] (2008). Nature <strong>452</strong>: 478-482</ref>J-RGCs <del class="diffchange diffchange-inline">have </del>asymmetric [[Dendrite#Dendritic_Arbor|dendritic arbors]] aligned in a dorsal-to-ventral direction across the retina<del class="diffchange diffchange-inline">. Those J-RGCs with markedly asymmetric dendritic arbors also have asymmetric receptive fields</del>. This was the first cell type in the retina to be classified based on the presence of a molecular biomarker.</div></td><td class='diff-marker'>+</td><td style="color:black; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div>'''J-RGCs''' are retinal ganglion cells defined by their expression of the protein [https://en.wikipedia.org/wiki/JAM2 Junction Adhesion Molecule B (JAM-B)]. J-RGCs are OFF RGCs that are direction selective, responding specifically to upward motion in the visual field.<ref name="kim2008">In-Jung Kim et al. [http://hebb.mit.edu/courses/connectomics/Kim%20molecular%20identification%20retinal%20cell%20type%20upward%20motion%2008.pdf Molecular identification of a retinal cell type that responds to upward motion] (2008). Nature <strong>452</strong>: 478-482</ref> J-RGCs <ins class="diffchange diffchange-inline">can be recognized by their </ins>asymmetric [[Dendrite#Dendritic_Arbor|dendritic arbors]] aligned in a dorsal-to-ventral direction across the retina. This was the first cell type in the retina to be classified based on the presence of a molecular biomarker.</div></td></tr>
<tr><td class='diff-marker'> </td><td style="background-color: #f9f9f9; color: #333333; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #e6e6e6; vertical-align: top; white-space: pre-wrap;"></td><td class='diff-marker'> </td><td style="background-color: #f9f9f9; color: #333333; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #e6e6e6; vertical-align: top; white-space: pre-wrap;"></td></tr>
<tr><td class='diff-marker'> </td><td style="background-color: #f9f9f9; color: #333333; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #e6e6e6; vertical-align: top; white-space: pre-wrap;"><div>== Anatomy ==</div></td><td class='diff-marker'> </td><td style="background-color: #f9f9f9; color: #333333; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #e6e6e6; vertical-align: top; white-space: pre-wrap;"><div>== Anatomy ==</div></td></tr>
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Miopio
https://wiki.eyewire.org/index.php?title=J-RGC&diff=6771&oldid=prev
Miopio at 17:31, 24 September 2015
2015-09-24T17:31:25Z
<p></p>
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<td colspan='2' style="background-color: white; color:black; text-align: center;">Revision as of 17:31, 24 September 2015</td>
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<tr><td class='diff-marker'> </td><td style="background-color: #f9f9f9; color: #333333; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #e6e6e6; vertical-align: top; white-space: pre-wrap;"><div><references /></div></td><td class='diff-marker'> </td><td style="background-color: #f9f9f9; color: #333333; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #e6e6e6; vertical-align: top; white-space: pre-wrap;"><div><references /></div></td></tr>
<tr><td colspan="2"> </td><td class='diff-marker'>+</td><td style="color:black; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div><ins style="font-weight: bold; text-decoration: none;"></ins></div></td></tr>
<tr><td colspan="2"> </td><td class='diff-marker'>+</td><td style="color:black; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div><ins style="font-weight: bold; text-decoration: none;">{{Retinal Neuron Types}}</ins></div></td></tr>
</table>
Miopio
https://wiki.eyewire.org/index.php?title=J-RGC&diff=6770&oldid=prev
Miopio at 17:30, 24 September 2015
2015-09-24T17:30:59Z
<p></p>
<table class='diff diff-contentalign-left'>
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<td colspan='2' style="background-color: white; color:black; text-align: center;">Revision as of 17:30, 24 September 2015</td>
</tr><tr><td colspan="2" class="diff-lineno" id="L1" >Line 1:</td>
<td colspan="2" class="diff-lineno">Line 1:</td></tr>
<tr><td class='diff-marker'> </td><td style="background-color: #f9f9f9; color: #333333; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #e6e6e6; vertical-align: top; white-space: pre-wrap;"><div>[[Image:jamb010_side.png|thumb|right|420px|A side view of a JAM-B cell showing the asymmetrical dendritic field.<ref name="kim2008" />]]</div></td><td class='diff-marker'> </td><td style="background-color: #f9f9f9; color: #333333; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #e6e6e6; vertical-align: top; white-space: pre-wrap;"><div>[[Image:jamb010_side.png|thumb|right|420px|A side view of a JAM-B cell showing the asymmetrical dendritic field.<ref name="kim2008" />]]</div></td></tr>
<tr><td class='diff-marker'> </td><td style="background-color: #f9f9f9; color: #333333; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #e6e6e6; vertical-align: top; white-space: pre-wrap;"></td><td class='diff-marker'> </td><td style="background-color: #f9f9f9; color: #333333; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #e6e6e6; vertical-align: top; white-space: pre-wrap;"></td></tr>
<tr><td class='diff-marker'>−</td><td style="color:black; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div>'''J-RGCs''' are retinal ganglion cells defined by their expression of the protein [https://en.wikipedia.org/wiki/JAM2 Junction Adhesion Molecule B (JAM-B)]. J-RGCs are OFF RGCs that are direction selective, responding specifically to upward motion. <ref name="kim2008">In-Jung Kim et al. [http://hebb.mit.edu/courses/connectomics/Kim%20molecular%20identification%20retinal%20cell%20type%20upward%20motion%2008.pdf Molecular identification of a retinal cell type that responds to upward motion] (2008). Nature <strong>452</strong>: 478-482</ref>J-RGCs have asymmetric [[Dendrite#Dendritic_Arbor|dendritic arbors]] aligned in a dorsal-to-ventral direction across the retina. Those J-RGCs with markedly asymmetric dendritic arbors also have asymmetric receptive fields. This was the first cell type in the retina to be classified based on the presence of a molecular biomarker.</div></td><td class='diff-marker'>+</td><td style="color:black; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div>'''J-RGCs''' are retinal ganglion cells defined by their expression of the protein [https://en.wikipedia.org/wiki/JAM2 Junction Adhesion Molecule B (JAM-B)]. J-RGCs are OFF RGCs that are direction selective, responding specifically to upward motion <ins class="diffchange diffchange-inline">in the visual field</ins>. <ref name="kim2008">In-Jung Kim et al. [http://hebb.mit.edu/courses/connectomics/Kim%20molecular%20identification%20retinal%20cell%20type%20upward%20motion%2008.pdf Molecular identification of a retinal cell type that responds to upward motion] (2008). Nature <strong>452</strong>: 478-482</ref>J-RGCs have asymmetric [[Dendrite#Dendritic_Arbor|dendritic arbors]] aligned in a dorsal-to-ventral direction across the retina. Those J-RGCs with markedly asymmetric dendritic arbors also have asymmetric receptive fields. This was the first cell type in the retina to be classified based on the presence of a molecular biomarker.</div></td></tr>
<tr><td class='diff-marker'> </td><td style="background-color: #f9f9f9; color: #333333; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #e6e6e6; vertical-align: top; white-space: pre-wrap;"></td><td class='diff-marker'> </td><td style="background-color: #f9f9f9; color: #333333; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #e6e6e6; vertical-align: top; white-space: pre-wrap;"></td></tr>
<tr><td class='diff-marker'> </td><td style="background-color: #f9f9f9; color: #333333; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #e6e6e6; vertical-align: top; white-space: pre-wrap;"><div>== Anatomy ==</div></td><td class='diff-marker'> </td><td style="background-color: #f9f9f9; color: #333333; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #e6e6e6; vertical-align: top; white-space: pre-wrap;"><div>== Anatomy ==</div></td></tr>
</table>
Miopio
https://wiki.eyewire.org/index.php?title=J-RGC&diff=6769&oldid=prev
Miopio at 17:28, 24 September 2015
2015-09-24T17:28:02Z
<p></p>
<table class='diff diff-contentalign-left'>
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<col class='diff-marker' />
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<td colspan='2' style="background-color: white; color:black; text-align: center;">← Older revision</td>
<td colspan='2' style="background-color: white; color:black; text-align: center;">Revision as of 17:28, 24 September 2015</td>
</tr><tr><td colspan="2" class="diff-lineno" id="L1" >Line 1:</td>
<td colspan="2" class="diff-lineno">Line 1:</td></tr>
<tr><td class='diff-marker'> </td><td style="background-color: #f9f9f9; color: #333333; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #e6e6e6; vertical-align: top; white-space: pre-wrap;"><div>[[Image:jamb010_side.png|thumb|right|420px|A side view of a JAM-B cell showing the asymmetrical dendritic field.<ref name="kim2008" />]]</div></td><td class='diff-marker'> </td><td style="background-color: #f9f9f9; color: #333333; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #e6e6e6; vertical-align: top; white-space: pre-wrap;"><div>[[Image:jamb010_side.png|thumb|right|420px|A side view of a JAM-B cell showing the asymmetrical dendritic field.<ref name="kim2008" />]]</div></td></tr>
<tr><td class='diff-marker'> </td><td style="background-color: #f9f9f9; color: #333333; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #e6e6e6; vertical-align: top; white-space: pre-wrap;"></td><td class='diff-marker'> </td><td style="background-color: #f9f9f9; color: #333333; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #e6e6e6; vertical-align: top; white-space: pre-wrap;"></td></tr>
<tr><td class='diff-marker'>−</td><td style="color:black; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div>'''J-RGCs''' are retinal ganglion cells defined by their expression of the protein [https://en.wikipedia.org/wiki/JAM2 Junction Adhesion Molecule B (JAM-B)]. <del class="diffchange diffchange-inline">JAM-B cells share many functional and structural traits in addition to the presence of the JAM-B molecular biomarker. For example, most </del>J-RGCs <del class="diffchange diffchange-inline">have asymmetric [[Dendrite#Dendritic_Arbor|dendritic arbors]] aligned in a dorsal-to-ventral direction across the retina. Those J-RGCs with markedly asymmetric dendritic arbors also have asymmetric receptive fields. J-</del>RGCs are direction<del class="diffchange diffchange-inline">-</del>selective, responding specifically to upward motion<del class="diffchange diffchange-inline">. Furthermore, they are all OFF RGCs, meaning they respond to a decrease of light in the receptive field center, or to the trailing rather than the leading edge of a moving bright stimulus</del>.<ref name="kim2008">In-Jung Kim et al. [http://hebb.mit.edu/courses/connectomics/Kim%20molecular%20identification%20retinal%20cell%20type%20upward%20motion%2008.pdf Molecular identification of a retinal cell type that responds to upward motion] (2008). Nature <strong>452</strong>: 478-482</ref>This was the first cell type in the retina to be classified based on the presence of a molecular biomarker.</div></td><td class='diff-marker'>+</td><td style="color:black; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div>'''J-RGCs''' are retinal ganglion cells defined by their expression of the protein [https://en.wikipedia.org/wiki/JAM2 Junction Adhesion Molecule B (JAM-B)]. J-RGCs <ins class="diffchange diffchange-inline">are OFF </ins>RGCs <ins class="diffchange diffchange-inline">that </ins>are direction selective, responding specifically to upward motion. <ref name="kim2008">In-Jung Kim et al. [http://hebb.mit.edu/courses/connectomics/Kim%20molecular%20identification%20retinal%20cell%20type%20upward%20motion%2008.pdf Molecular identification of a retinal cell type that responds to upward motion] (2008). Nature <strong>452</strong>: 478-482</ref><ins class="diffchange diffchange-inline">J-RGCs have asymmetric [[Dendrite#Dendritic_Arbor|dendritic arbors]] aligned in a dorsal-to-ventral direction across the retina. Those J-RGCs with markedly asymmetric dendritic arbors also have asymmetric receptive fields. </ins>This was the first cell type in the retina to be classified based on the presence of a molecular biomarker.</div></td></tr>
<tr><td class='diff-marker'> </td><td style="background-color: #f9f9f9; color: #333333; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #e6e6e6; vertical-align: top; white-space: pre-wrap;"></td><td class='diff-marker'> </td><td style="background-color: #f9f9f9; color: #333333; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #e6e6e6; vertical-align: top; white-space: pre-wrap;"></td></tr>
<tr><td class='diff-marker'> </td><td style="background-color: #f9f9f9; color: #333333; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #e6e6e6; vertical-align: top; white-space: pre-wrap;"><div>== Anatomy ==</div></td><td class='diff-marker'> </td><td style="background-color: #f9f9f9; color: #333333; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #e6e6e6; vertical-align: top; white-space: pre-wrap;"><div>== Anatomy ==</div></td></tr>
</table>
Miopio