Difference between revisions of "J-RGC"
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− | JAM-B cells are a subcategory of retinal ganglion cell in mice which respond specifically to upward motion. | + | JAM-B cells are a molecularly defined subcategory of retinal ganglion cell in mice which respond specifically to upward motion. |
Revision as of 12:16, 24 March 2012
JAM-B cells are a molecularly defined subcategory of retinal ganglion cell in mice which respond specifically to upward motion.
Contents
Introduction
JAM-B cells are named after Junctional Adhesion Molecule B, the molecular marker first used to define them as a distinct subset of retinal ganglion cells. JAM-B share many traits in addition to the presence of this molecule. They are all OFF RGCs, with asymmetric dendritic arbors aligned in a dorsal-to-ventral direction across the retina (source: Kim et al.) Their deepest importance to the study and categorization of cells in the retina lies in that they were the first RGC to be classified using a molecular marker.