https://wiki.eyewire.org/index.php?title=index.php&&title=E2198/es&feed=atom&action=historyE2198/es - Revision history2024-03-28T20:15:22ZRevision history for this page on the wikiMediaWiki 1.25.2https://wiki.eyewire.org/index.php?title=E2198/es&diff=12563&oldid=prevHawaiisunfun at 16:34, 20 July 20192019-07-20T16:34:43Z<p></p>
<table class='diff diff-contentalign-left'>
<col class='diff-marker' />
<col class='diff-content' />
<col class='diff-marker' />
<col class='diff-content' />
<tr style='vertical-align: top;'>
<td colspan='2' style="background-color: white; color:black; text-align: center;">← Older revision</td>
<td colspan='2' style="background-color: white; color:black; text-align: center;">Revision as of 16:34, 20 July 2019</td>
</tr><tr><td colspan="2" class="diff-lineno" id="L1" >Line 1:</td>
<td colspan="2" class="diff-lineno">Line 1:</td></tr>
<tr><td class='diff-marker'>−</td><td style="color:black; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div>yeWire se basa en las imágenes que se adquirieron en el Instituto Max Planck para la Investigación Médica en Heidelberg, Alemania. Este conjunto de datos, conocido como E2198, fue la base de la especificidad de cableado en el circuito de selectividad de dirección de la retina. <ref nombre="Briggman">Especificidad de cableado en el circuito de selectividad de dirección de la retina. K. L. Briggman M. Helmstaedter W. Denk. Nature volume471 pgs183-188 http://www.nature.com/nature/journal/v471/n7337/full/nature09818.html </ref> La fuente retina se obtuvo de un adulto natural adaptado a la oscuridad (C57BL/6) ratón.</div></td><td class='diff-marker'>+</td><td style="color:black; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div>yeWire se basa en las imágenes que se adquirieron en el Instituto Max Planck para la Investigación Médica en Heidelberg, Alemania. Este conjunto de datos, conocido como E2198, fue la base de la especificidad de cableado en el circuito de selectividad de dirección de la retina.<ref nombre="Briggman">Especificidad de cableado en el circuito de selectividad de dirección de la retina. K. L. Briggman M. Helmstaedter W. Denk. Nature volume471 pgs183-188 http://www.nature.com/nature/journal/v471/n7337/full/nature09818.html </ref> La fuente retina se obtuvo de un adulto natural adaptado a la oscuridad (C57BL/6) ratón.</div></td></tr>
<tr><td class='diff-marker'> </td><td style="background-color: #f9f9f9; color: #333333; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #e6e6e6; vertical-align: top; white-space: pre-wrap;"></td><td class='diff-marker'> </td><td style="background-color: #f9f9f9; color: #333333; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #e6e6e6; vertical-align: top; white-space: pre-wrap;"></td></tr>
<tr><td class='diff-marker'> </td><td style="background-color: #f9f9f9; color: #333333; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #e6e6e6; vertical-align: top; white-space: pre-wrap;"><div>Los investigadores midieron tanto la actividad neural como la conectividad en la misma retina mediante la aplicación de dos métodos de imagen uno tras otro: microscopía de dos fotones (2P) y [[microscopía electrónica de barrido de cara en serie (SBFSEM)|microscopía electrónica de barrido de cara en serie (SBFSEM)]].</div></td><td class='diff-marker'> </td><td style="background-color: #f9f9f9; color: #333333; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #e6e6e6; vertical-align: top; white-space: pre-wrap;"><div>Los investigadores midieron tanto la actividad neural como la conectividad en la misma retina mediante la aplicación de dos métodos de imagen uno tras otro: microscopía de dos fotones (2P) y [[microscopía electrónica de barrido de cara en serie (SBFSEM)|microscopía electrónica de barrido de cara en serie (SBFSEM)]].</div></td></tr>
</table>Hawaiisunfunhttps://wiki.eyewire.org/index.php?title=E2198/es&diff=12561&oldid=prevHawaiisunfun: Created page with "== Referencias == <references />"2019-07-20T16:33:56Z<p>Created page with "== Referencias == <references />"</p>
<table class='diff diff-contentalign-left'>
<col class='diff-marker' />
<col class='diff-content' />
<col class='diff-marker' />
<col class='diff-content' />
<tr style='vertical-align: top;'>
<td colspan='2' style="background-color: white; color:black; text-align: center;">← Older revision</td>
<td colspan='2' style="background-color: white; color:black; text-align: center;">Revision as of 16:33, 20 July 2019</td>
</tr><tr><td colspan="2" class="diff-lineno" id="L30" >Line 30:</td>
<td colspan="2" class="diff-lineno">Line 30:</td></tr>
<tr><td class='diff-marker'> </td><td style="background-color: #f9f9f9; color: #333333; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #e6e6e6; vertical-align: top; white-space: pre-wrap;"><div>https://drive.google.com/folderview?id=0B1ZqbPNMA3DafjJfMFJ5dlFhQWJrQ1hsZWlRVC1yTnpET29NV0Y0MC1HMkVtc0tDTmxDSEE&usp=sharing</div></td><td class='diff-marker'> </td><td style="background-color: #f9f9f9; color: #333333; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #e6e6e6; vertical-align: top; white-space: pre-wrap;"><div>https://drive.google.com/folderview?id=0B1ZqbPNMA3DafjJfMFJ5dlFhQWJrQ1hsZWlRVC1yTnpET29NV0Y0MC1HMkVtc0tDTmxDSEE&usp=sharing</div></td></tr>
<tr><td class='diff-marker'> </td><td style="background-color: #f9f9f9; color: #333333; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #e6e6e6; vertical-align: top; white-space: pre-wrap;"></td><td class='diff-marker'> </td><td style="background-color: #f9f9f9; color: #333333; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #e6e6e6; vertical-align: top; white-space: pre-wrap;"></td></tr>
<tr><td class='diff-marker'>−</td><td style="color:black; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div>== <del class="diffchange diffchange-inline">References </del>==</div></td><td class='diff-marker'>+</td><td style="color:black; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div>== <ins class="diffchange diffchange-inline">Referencias </ins>==</div></td></tr>
<tr><td class='diff-marker'> </td><td style="background-color: #f9f9f9; color: #333333; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #e6e6e6; vertical-align: top; white-space: pre-wrap;"><div><references /></div></td><td class='diff-marker'> </td><td style="background-color: #f9f9f9; color: #333333; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #e6e6e6; vertical-align: top; white-space: pre-wrap;"><div><references /></div></td></tr>
</table>Hawaiisunfunhttps://wiki.eyewire.org/index.php?title=E2198/es&diff=12559&oldid=prevHawaiisunfun: Created page with "Puede acceder a los datos de entrenamiento de la red neuronal convolucional original aquí:"2019-07-20T16:33:34Z<p>Created page with "Puede acceder a los datos de entrenamiento de la red neuronal convolucional original aquí:"</p>
<table class='diff diff-contentalign-left'>
<col class='diff-marker' />
<col class='diff-content' />
<col class='diff-marker' />
<col class='diff-content' />
<tr style='vertical-align: top;'>
<td colspan='2' style="background-color: white; color:black; text-align: center;">← Older revision</td>
<td colspan='2' style="background-color: white; color:black; text-align: center;">Revision as of 16:33, 20 July 2019</td>
</tr><tr><td colspan="2" class="diff-lineno" id="L26" >Line 26:</td>
<td colspan="2" class="diff-lineno">Line 26:</td></tr>
<tr><td class='diff-marker'> </td><td style="background-color: #f9f9f9; color: #333333; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #e6e6e6; vertical-align: top; white-space: pre-wrap;"><div>== Datos de entrenamiento ==</div></td><td class='diff-marker'> </td><td style="background-color: #f9f9f9; color: #333333; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #e6e6e6; vertical-align: top; white-space: pre-wrap;"><div>== Datos de entrenamiento ==</div></td></tr>
<tr><td class='diff-marker'> </td><td style="background-color: #f9f9f9; color: #333333; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #e6e6e6; vertical-align: top; white-space: pre-wrap;"></td><td class='diff-marker'> </td><td style="background-color: #f9f9f9; color: #333333; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #e6e6e6; vertical-align: top; white-space: pre-wrap;"></td></tr>
<tr><td class='diff-marker'>−</td><td style="color:black; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div><del class="diffchange diffchange-inline">You can access the </del>original <del class="diffchange diffchange-inline">convolutional neural network training data here</del>:  </div></td><td class='diff-marker'>+</td><td style="color:black; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div><ins class="diffchange diffchange-inline">Puede acceder a los datos de entrenamiento de la red neuronal convolucional </ins>original <ins class="diffchange diffchange-inline">aquí</ins>:  </div></td></tr>
<tr><td class='diff-marker'> </td><td style="background-color: #f9f9f9; color: #333333; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #e6e6e6; vertical-align: top; white-space: pre-wrap;"></td><td class='diff-marker'> </td><td style="background-color: #f9f9f9; color: #333333; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #e6e6e6; vertical-align: top; white-space: pre-wrap;"></td></tr>
<tr><td class='diff-marker'> </td><td style="background-color: #f9f9f9; color: #333333; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #e6e6e6; vertical-align: top; white-space: pre-wrap;"><div>https://drive.google.com/folderview?id=0B1ZqbPNMA3DafjJfMFJ5dlFhQWJrQ1hsZWlRVC1yTnpET29NV0Y0MC1HMkVtc0tDTmxDSEE&usp=sharing</div></td><td class='diff-marker'> </td><td style="background-color: #f9f9f9; color: #333333; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #e6e6e6; vertical-align: top; white-space: pre-wrap;"><div>https://drive.google.com/folderview?id=0B1ZqbPNMA3DafjJfMFJ5dlFhQWJrQ1hsZWlRVC1yTnpET29NV0Y0MC1HMkVtc0tDTmxDSEE&usp=sharing</div></td></tr>
</table>Hawaiisunfunhttps://wiki.eyewire.org/index.php?title=E2198/es&diff=12557&oldid=prevHawaiisunfun: Created page with "== Datos de entrenamiento =="2019-07-20T16:33:22Z<p>Created page with "== Datos de entrenamiento =="</p>
<table class='diff diff-contentalign-left'>
<col class='diff-marker' />
<col class='diff-content' />
<col class='diff-marker' />
<col class='diff-content' />
<tr style='vertical-align: top;'>
<td colspan='2' style="background-color: white; color:black; text-align: center;">← Older revision</td>
<td colspan='2' style="background-color: white; color:black; text-align: center;">Revision as of 16:33, 20 July 2019</td>
</tr><tr><td colspan="2" class="diff-lineno" id="L24" >Line 24:</td>
<td colspan="2" class="diff-lineno">Line 24:</td></tr>
<tr><td class='diff-marker'> </td><td style="background-color: #f9f9f9; color: #333333; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #e6e6e6; vertical-align: top; white-space: pre-wrap;"><div>Este estudio se basó en reconstrucciones de solo 30 neuronas en E2198. Claramente, hay mucho más que aprender de este conjunto de datos, que contiene miles de neuronas.</div></td><td class='diff-marker'> </td><td style="background-color: #f9f9f9; color: #333333; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #e6e6e6; vertical-align: top; white-space: pre-wrap;"><div>Este estudio se basó en reconstrucciones de solo 30 neuronas en E2198. Claramente, hay mucho más que aprender de este conjunto de datos, que contiene miles de neuronas.</div></td></tr>
<tr><td class='diff-marker'> </td><td style="background-color: #f9f9f9; color: #333333; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #e6e6e6; vertical-align: top; white-space: pre-wrap;"></td><td class='diff-marker'> </td><td style="background-color: #f9f9f9; color: #333333; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #e6e6e6; vertical-align: top; white-space: pre-wrap;"></td></tr>
<tr><td class='diff-marker'>−</td><td style="color:black; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div>== <del class="diffchange diffchange-inline">Training Data </del>==</div></td><td class='diff-marker'>+</td><td style="color:black; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div>== <ins class="diffchange diffchange-inline">Datos de entrenamiento </ins>==</div></td></tr>
<tr><td class='diff-marker'> </td><td style="background-color: #f9f9f9; color: #333333; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #e6e6e6; vertical-align: top; white-space: pre-wrap;"></td><td class='diff-marker'> </td><td style="background-color: #f9f9f9; color: #333333; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #e6e6e6; vertical-align: top; white-space: pre-wrap;"></td></tr>
<tr><td class='diff-marker'> </td><td style="background-color: #f9f9f9; color: #333333; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #e6e6e6; vertical-align: top; white-space: pre-wrap;"><div>You can access the original convolutional neural network training data here:  </div></td><td class='diff-marker'> </td><td style="background-color: #f9f9f9; color: #333333; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #e6e6e6; vertical-align: top; white-space: pre-wrap;"><div>You can access the original convolutional neural network training data here:  </div></td></tr>
</table>Hawaiisunfunhttps://wiki.eyewire.org/index.php?title=E2198/es&diff=12555&oldid=prevHawaiisunfun: Created page with "Este estudio se basó en reconstrucciones de solo 30 neuronas en E2198. Claramente, hay mucho más que aprender de este conjunto de datos, que contiene miles de neuronas."2019-07-20T16:33:06Z<p>Created page with "Este estudio se basó en reconstrucciones de solo 30 neuronas en E2198. Claramente, hay mucho más que aprender de este conjunto de datos, que contiene miles de neuronas."</p>
<table class='diff diff-contentalign-left'>
<col class='diff-marker' />
<col class='diff-content' />
<col class='diff-marker' />
<col class='diff-content' />
<tr style='vertical-align: top;'>
<td colspan='2' style="background-color: white; color:black; text-align: center;">← Older revision</td>
<td colspan='2' style="background-color: white; color:black; text-align: center;">Revision as of 16:33, 20 July 2019</td>
</tr><tr><td colspan="2" class="diff-lineno" id="L22" >Line 22:</td>
<td colspan="2" class="diff-lineno">Line 22:</td></tr>
<tr><td class='diff-marker'> </td><td style="background-color: #f9f9f9; color: #333333; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #e6e6e6; vertical-align: top; white-space: pre-wrap;"><div>De este análisis, los investigadores derivaron una regla que gobierna la conectividad DSGC-[[Células Amacrina Estelar|SAC]]. Todas las dendritas y [DSGC de [Células Amacrina Estelar|SAC]] responden selectivamente al movimiento ("preferido") en alguna dirección. Los investigadores encontraron que los DSGC tienden a recibir más sinapsis de dendritas [[Células Amacrina Estelar|SAC]] con la dirección opuesta preferida, lo que evidencia la especificidad de las conexiones. En principio, un DSGC podría recibir indiscriminadamente sinapsis de todas las dendritas vecinas [[Células Amacrina Estelar|SAC]], que generalmente abarcan una diversidad de direcciones preferidas, pero este no es el caso. La regla de conectividad sugiere que un DSGC "hereda" su selectividad de dirección de sus entradas, ya que [[Células Amacrina Estelar|SAC]] hace sinapsis inhibitorias (inversión de signo) en DSGCs.</div></td><td class='diff-marker'> </td><td style="background-color: #f9f9f9; color: #333333; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #e6e6e6; vertical-align: top; white-space: pre-wrap;"><div>De este análisis, los investigadores derivaron una regla que gobierna la conectividad DSGC-[[Células Amacrina Estelar|SAC]]. Todas las dendritas y [DSGC de [Células Amacrina Estelar|SAC]] responden selectivamente al movimiento ("preferido") en alguna dirección. Los investigadores encontraron que los DSGC tienden a recibir más sinapsis de dendritas [[Células Amacrina Estelar|SAC]] con la dirección opuesta preferida, lo que evidencia la especificidad de las conexiones. En principio, un DSGC podría recibir indiscriminadamente sinapsis de todas las dendritas vecinas [[Células Amacrina Estelar|SAC]], que generalmente abarcan una diversidad de direcciones preferidas, pero este no es el caso. La regla de conectividad sugiere que un DSGC "hereda" su selectividad de dirección de sus entradas, ya que [[Células Amacrina Estelar|SAC]] hace sinapsis inhibitorias (inversión de signo) en DSGCs.</div></td></tr>
<tr><td class='diff-marker'> </td><td style="background-color: #f9f9f9; color: #333333; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #e6e6e6; vertical-align: top; white-space: pre-wrap;"></td><td class='diff-marker'> </td><td style="background-color: #f9f9f9; color: #333333; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #e6e6e6; vertical-align: top; white-space: pre-wrap;"></td></tr>
<tr><td class='diff-marker'>−</td><td style="color:black; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div><del class="diffchange diffchange-inline">This study was based on reconstructions of just </del>30 <del class="diffchange diffchange-inline">neurons in </del>E2198. <del class="diffchange diffchange-inline">Clearly there is much more to be learned from this dataset</del>, <del class="diffchange diffchange-inline">which contains thousands of neurons</del>.</div></td><td class='diff-marker'>+</td><td style="color:black; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div><ins class="diffchange diffchange-inline">Este estudio se basó en reconstrucciones de solo </ins>30 <ins class="diffchange diffchange-inline">neuronas en </ins>E2198. <ins class="diffchange diffchange-inline">Claramente</ins>, <ins class="diffchange diffchange-inline">hay mucho más que aprender de este conjunto de datos, que contiene miles de neuronas</ins>.</div></td></tr>
<tr><td class='diff-marker'> </td><td style="background-color: #f9f9f9; color: #333333; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #e6e6e6; vertical-align: top; white-space: pre-wrap;"></td><td class='diff-marker'> </td><td style="background-color: #f9f9f9; color: #333333; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #e6e6e6; vertical-align: top; white-space: pre-wrap;"></td></tr>
<tr><td class='diff-marker'> </td><td style="background-color: #f9f9f9; color: #333333; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #e6e6e6; vertical-align: top; white-space: pre-wrap;"><div>== Training Data ==</div></td><td class='diff-marker'> </td><td style="background-color: #f9f9f9; color: #333333; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #e6e6e6; vertical-align: top; white-space: pre-wrap;"><div>== Training Data ==</div></td></tr>
</table>Hawaiisunfunhttps://wiki.eyewire.org/index.php?title=E2198/es&diff=12553&oldid=prevHawaiisunfun: Created page with "De este análisis, los investigadores derivaron una regla que gobierna la conectividad DSGC-SAC. Todas las dendritas y [DSGC de [Células Amacrin..."2019-07-20T16:32:51Z<p>Created page with "De este análisis, los investigadores derivaron una regla que gobierna la conectividad DSGC-<a href="/index.php?title=C%C3%A9lulas_Amacrina_Estelar&action=edit&redlink=1" class="new" title="Células Amacrina Estelar (page does not exist)">SAC</a>. Todas las dendritas y [DSGC de [Células Amacrin..."</p>
<table class='diff diff-contentalign-left'>
<col class='diff-marker' />
<col class='diff-content' />
<col class='diff-marker' />
<col class='diff-content' />
<tr style='vertical-align: top;'>
<td colspan='2' style="background-color: white; color:black; text-align: center;">← Older revision</td>
<td colspan='2' style="background-color: white; color:black; text-align: center;">Revision as of 16:32, 20 July 2019</td>
</tr><tr><td colspan="2" class="diff-lineno" id="L20" >Line 20:</td>
<td colspan="2" class="diff-lineno">Line 20:</td></tr>
<tr><td class='diff-marker'> </td><td style="background-color: #f9f9f9; color: #333333; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #e6e6e6; vertical-align: top; white-space: pre-wrap;"><div>[[Image:e2198_contactb.png|thumb|left|600px|Los contactos varicosos (a,b) son sinapsis, como lo demuestra la presencia de vesículas (b) en un conjunto de datos teñidos convencionalmente. Los contactos incidentales (c,d) no son sinapsis, como lo demuestra la ausencia de vesículas (d) en un conjunto de datos teñidos convencionalmente. Debido a su alta resolución, la EM revela cuando se interpone una lámina glial delgada entre dos neuronas (e), una situación que parece ser un punto de contacto entre las dos neuronas en una imagen microscópica de luz.]]</div></td><td class='diff-marker'> </td><td style="background-color: #f9f9f9; color: #333333; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #e6e6e6; vertical-align: top; white-space: pre-wrap;"><div>[[Image:e2198_contactb.png|thumb|left|600px|Los contactos varicosos (a,b) son sinapsis, como lo demuestra la presencia de vesículas (b) en un conjunto de datos teñidos convencionalmente. Los contactos incidentales (c,d) no son sinapsis, como lo demuestra la ausencia de vesículas (d) en un conjunto de datos teñidos convencionalmente. Debido a su alta resolución, la EM revela cuando se interpone una lámina glial delgada entre dos neuronas (e), una situación que parece ser un punto de contacto entre las dos neuronas en una imagen microscópica de luz.]]</div></td></tr>
<tr><td class='diff-marker'> </td><td style="background-color: #f9f9f9; color: #333333; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #e6e6e6; vertical-align: top; white-space: pre-wrap;"></td><td class='diff-marker'> </td><td style="background-color: #f9f9f9; color: #333333; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #e6e6e6; vertical-align: top; white-space: pre-wrap;"></td></tr>
<tr><td class='diff-marker'>−</td><td style="color:black; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div><del class="diffchange diffchange-inline">From this analysis</del>, <del class="diffchange diffchange-inline">the researchers derived a rule governing </del>DSGC-[[<del class="diffchange diffchange-inline">Starburst Amacrine Cell</del>|SAC]] <del class="diffchange diffchange-inline">connectivity</del>. <del class="diffchange diffchange-inline">All </del>[[<del class="diffchange diffchange-inline">Starburst Amacrine Cell</del>|SAC]] <del class="diffchange diffchange-inline">dendrites and DSGCs respond selectively to </del>("<del class="diffchange diffchange-inline">prefer</del>") <del class="diffchange diffchange-inline">motion in some direction</del>. <del class="diffchange diffchange-inline">The researchers found that DSGCs tend to receive more synapses from </del>[[<del class="diffchange diffchange-inline">Starburst Amacrine Cell</del>|SAC]] <del class="diffchange diffchange-inline">dendrites with the opposite preferred direction</del>, <del class="diffchange diffchange-inline">which is evidence for specificity of connections</del>. <del class="diffchange diffchange-inline">In principle</del>, <del class="diffchange diffchange-inline">a </del>DSGC <del class="diffchange diffchange-inline">could indiscriminately receive synapses from all neighboring </del>[[<del class="diffchange diffchange-inline">Starburst Amacrine Cell</del>|SAC]] <del class="diffchange diffchange-inline">dendrites</del>, <del class="diffchange diffchange-inline">which generally encompass a diversity of preferred directions</del>, <del class="diffchange diffchange-inline">but this is not the case</del>. <del class="diffchange diffchange-inline">The rule of connectivity suggests that a </del>DSGC "<del class="diffchange diffchange-inline">inherits</del>" <del class="diffchange diffchange-inline">its direction selectivity from its inputs</del>, <del class="diffchange diffchange-inline">since </del>[[<del class="diffchange diffchange-inline">Starburst Amacrine Cell</del>|SAC]]<del class="diffchange diffchange-inline">s make inhibitory </del>(<del class="diffchange diffchange-inline">sign-inverting</del>) <del class="diffchange diffchange-inline">synapses onto </del>DSGCs.</div></td><td class='diff-marker'>+</td><td style="color:black; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div><ins class="diffchange diffchange-inline">De este análisis</ins>, <ins class="diffchange diffchange-inline">los investigadores derivaron una regla que gobierna la conectividad </ins>DSGC-[[<ins class="diffchange diffchange-inline">Células Amacrina Estelar</ins>|SAC]]. <ins class="diffchange diffchange-inline">Todas las dendritas y </ins>[<ins class="diffchange diffchange-inline">DSGC de </ins>[<ins class="diffchange diffchange-inline">Células Amacrina Estelar</ins>|SAC]] <ins class="diffchange diffchange-inline">responden selectivamente al movimiento </ins>("<ins class="diffchange diffchange-inline">preferido</ins>") <ins class="diffchange diffchange-inline">en alguna dirección</ins>. <ins class="diffchange diffchange-inline">Los investigadores encontraron que los DSGC tienden a recibir más sinapsis de dendritas </ins>[[<ins class="diffchange diffchange-inline">Células Amacrina Estelar</ins>|SAC]] <ins class="diffchange diffchange-inline">con la dirección opuesta preferida</ins>, <ins class="diffchange diffchange-inline">lo que evidencia la especificidad de las conexiones</ins>. <ins class="diffchange diffchange-inline">En principio</ins>, <ins class="diffchange diffchange-inline">un </ins>DSGC <ins class="diffchange diffchange-inline">podría recibir indiscriminadamente sinapsis de todas las dendritas vecinas </ins>[[<ins class="diffchange diffchange-inline">Células Amacrina Estelar</ins>|SAC]], <ins class="diffchange diffchange-inline">que generalmente abarcan una diversidad de direcciones preferidas</ins>, <ins class="diffchange diffchange-inline">pero este no es el caso</ins>. <ins class="diffchange diffchange-inline">La regla de conectividad sugiere que un </ins>DSGC "<ins class="diffchange diffchange-inline">hereda</ins>" <ins class="diffchange diffchange-inline">su selectividad de dirección de sus entradas</ins>, <ins class="diffchange diffchange-inline">ya que </ins>[[<ins class="diffchange diffchange-inline">Células Amacrina Estelar</ins>|SAC]] <ins class="diffchange diffchange-inline">hace sinapsis inhibitorias </ins>(<ins class="diffchange diffchange-inline">inversión de signo</ins>) <ins class="diffchange diffchange-inline">en </ins>DSGCs.</div></td></tr>
<tr><td class='diff-marker'> </td><td style="background-color: #f9f9f9; color: #333333; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #e6e6e6; vertical-align: top; white-space: pre-wrap;"></td><td class='diff-marker'> </td><td style="background-color: #f9f9f9; color: #333333; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #e6e6e6; vertical-align: top; white-space: pre-wrap;"></td></tr>
<tr><td class='diff-marker'> </td><td style="background-color: #f9f9f9; color: #333333; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #e6e6e6; vertical-align: top; white-space: pre-wrap;"><div>This study was based on reconstructions of just 30 neurons in E2198. Clearly there is much more to be learned from this dataset, which contains thousands of neurons.</div></td><td class='diff-marker'> </td><td style="background-color: #f9f9f9; color: #333333; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #e6e6e6; vertical-align: top; white-space: pre-wrap;"><div>This study was based on reconstructions of just 30 neurons in E2198. Clearly there is much more to be learned from this dataset, which contains thousands of neurons.</div></td></tr>
</table>Hawaiisunfunhttps://wiki.eyewire.org/index.php?title=E2198/es&diff=12551&oldid=prevHawaiisunfun: Created page with "Como se muestra en las imágenes a continuación, las dendritas SAC y las dendritas DSGC se contactan entre sí. Sin embargo, no todos los pun..."2019-07-20T16:30:50Z<p>Created page with "Como se muestra en las imágenes a continuación, las dendritas <a href="/index.php?title=C%C3%A9lulas_Amacrina_de_Estelar&action=edit&redlink=1" class="new" title="Células Amacrina de Estelar (page does not exist)">SAC</a> y las dendritas DSGC se contactan entre sí. Sin embargo, no todos los pun..."</p>
<table class='diff diff-contentalign-left'>
<col class='diff-marker' />
<col class='diff-content' />
<col class='diff-marker' />
<col class='diff-content' />
<tr style='vertical-align: top;'>
<td colspan='2' style="background-color: white; color:black; text-align: center;">← Older revision</td>
<td colspan='2' style="background-color: white; color:black; text-align: center;">Revision as of 16:30, 20 July 2019</td>
</tr><tr><td colspan="2" class="diff-lineno" id="L17" >Line 17:</td>
<td colspan="2" class="diff-lineno">Line 17:</td></tr>
<tr><td class='diff-marker'> </td><td style="background-color: #f9f9f9; color: #333333; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #e6e6e6; vertical-align: top; white-space: pre-wrap;"><div>Los investigadores también reconstruyeron 24 [[Células Amacrina Estelar|células amacrina estelar]] (SACs), que se muestran en el Panel c. Estas celdas se dividen en dos clases: celdas ENCENDIDAS (n=11) que se estratifican en una subcapa de la IPL, y celdas APAGADAS (n=13) que se estratifican en otra subcapa. La comparación con el panel a muestra que [[Células Amacrina Estelar|SAC]] dendritas co-estratifican con dendritas DSGC, lo que sugiere que estos dos tipos de células podrían conectarse mediante [[Synapse|sinapsis]].</div></td><td class='diff-marker'> </td><td style="background-color: #f9f9f9; color: #333333; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #e6e6e6; vertical-align: top; white-space: pre-wrap;"><div>Los investigadores también reconstruyeron 24 [[Células Amacrina Estelar|células amacrina estelar]] (SACs), que se muestran en el Panel c. Estas celdas se dividen en dos clases: celdas ENCENDIDAS (n=11) que se estratifican en una subcapa de la IPL, y celdas APAGADAS (n=13) que se estratifican en otra subcapa. La comparación con el panel a muestra que [[Células Amacrina Estelar|SAC]] dendritas co-estratifican con dendritas DSGC, lo que sugiere que estos dos tipos de células podrían conectarse mediante [[Synapse|sinapsis]].</div></td></tr>
<tr><td class='diff-marker'> </td><td style="background-color: #f9f9f9; color: #333333; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #e6e6e6; vertical-align: top; white-space: pre-wrap;"></td><td class='diff-marker'> </td><td style="background-color: #f9f9f9; color: #333333; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #e6e6e6; vertical-align: top; white-space: pre-wrap;"></td></tr>
<tr><td class='diff-marker'>−</td><td style="color:black; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div><del class="diffchange diffchange-inline">As shown in the images below</del>, [[<del class="diffchange diffchange-inline">Starburst Amacrine Cell</del>|SAC]] <del class="diffchange diffchange-inline">dendrites and </del>DSGC <del class="diffchange diffchange-inline">dendrites indeed contact each other</del>. <del class="diffchange diffchange-inline">However</del>, <del class="diffchange diffchange-inline">not all points of contact are synapses</del>. <del class="diffchange diffchange-inline">The researchers conjectured that </del>"<del class="diffchange diffchange-inline">varicose</del>" <del class="diffchange diffchange-inline">contacts</del>, <del class="diffchange diffchange-inline">at which one dendrite seems to grasp or embrace another</del>, <del class="diffchange diffchange-inline">were actual synapses</del>, <del class="diffchange diffchange-inline">while </del>"<del class="diffchange diffchange-inline">incidental</del>" <del class="diffchange diffchange-inline">contacts were not synapses</del>.</div></td><td class='diff-marker'>+</td><td style="color:black; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div><ins class="diffchange diffchange-inline">Como se muestra en las imágenes a continuación</ins>, <ins class="diffchange diffchange-inline">las dendritas </ins>[[<ins class="diffchange diffchange-inline">Células Amacrina de Estelar</ins>|SAC]] <ins class="diffchange diffchange-inline">y las dendritas </ins>DSGC <ins class="diffchange diffchange-inline">se contactan entre sí</ins>. <ins class="diffchange diffchange-inline">Sin embargo</ins>, <ins class="diffchange diffchange-inline">no todos los puntos de contacto son sinapsis</ins>. <ins class="diffchange diffchange-inline">Los investigadores conjeturaron que los contactos </ins>"<ins class="diffchange diffchange-inline">varicosos</ins>", <ins class="diffchange diffchange-inline">en los que una dendrita parece agarrar o abrazar a otro</ins>, <ins class="diffchange diffchange-inline">eran sinapsis reales</ins>, <ins class="diffchange diffchange-inline">mientras que los contactos </ins>"<ins class="diffchange diffchange-inline">incidentales</ins>" <ins class="diffchange diffchange-inline">no eran sinapsis</ins>.</div></td></tr>
<tr><td class='diff-marker'>−</td><td style="color:black; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div>[[Image:e2198_contactb.png|thumb|left|600px|<del class="diffchange diffchange-inline">Varicose contacts </del>(a,b) <del class="diffchange diffchange-inline">are synapses</del>, <del class="diffchange diffchange-inline">as demonstrated by the presence of vesicles </del>(b) <del class="diffchange diffchange-inline">in a conventionally stained dataset</del>. <del class="diffchange diffchange-inline">Incidental contacts </del>(c,d) <del class="diffchange diffchange-inline">are not synapses</del>, <del class="diffchange diffchange-inline">as demonstrated by the absence of vesicles </del>(d) <del class="diffchange diffchange-inline">in </del>a <del class="diffchange diffchange-inline">conventionally stained dataset. Owing to its high resolution</del>, EM <del class="diffchange diffchange-inline">reveals when a thin </del>glial <del class="diffchange diffchange-inline">sheet is interposed between two neurons </del>(e), <del class="diffchange diffchange-inline">a situation that would appear to be a contact point between the two neurons in a light microscopic image</del>.]]</div></td><td class='diff-marker'>+</td><td style="color:black; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div>[[Image:e2198_contactb.png|thumb|left|600px|<ins class="diffchange diffchange-inline">Los contactos varicosos </ins>(a,b) <ins class="diffchange diffchange-inline">son sinapsis</ins>, <ins class="diffchange diffchange-inline">como lo demuestra la presencia de vesículas </ins>(b) <ins class="diffchange diffchange-inline">en un conjunto de datos teñidos convencionalmente</ins>. <ins class="diffchange diffchange-inline">Los contactos incidentales </ins>(c,d) <ins class="diffchange diffchange-inline">no son sinapsis</ins>, <ins class="diffchange diffchange-inline">como lo demuestra la ausencia de vesículas </ins>(d) <ins class="diffchange diffchange-inline">en un conjunto de datos teñidos convencionalmente. Debido </ins>a <ins class="diffchange diffchange-inline">su alta resolución</ins>, <ins class="diffchange diffchange-inline">la </ins>EM <ins class="diffchange diffchange-inline">revela cuando se interpone una lámina </ins>glial <ins class="diffchange diffchange-inline">delgada entre dos neuronas </ins>(e), <ins class="diffchange diffchange-inline">una situación que parece ser un punto de contacto entre las dos neuronas en una imagen microscópica de luz</ins>.]]</div></td></tr>
<tr><td class='diff-marker'> </td><td style="background-color: #f9f9f9; color: #333333; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #e6e6e6; vertical-align: top; white-space: pre-wrap;"></td><td class='diff-marker'> </td><td style="background-color: #f9f9f9; color: #333333; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #e6e6e6; vertical-align: top; white-space: pre-wrap;"></td></tr>
<tr><td class='diff-marker'> </td><td style="background-color: #f9f9f9; color: #333333; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #e6e6e6; vertical-align: top; white-space: pre-wrap;"><div>From this analysis, the researchers derived a rule governing DSGC-[[Starburst Amacrine Cell|SAC]] connectivity. All [[Starburst Amacrine Cell|SAC]] dendrites and DSGCs respond selectively to ("prefer") motion in some direction. The researchers found that DSGCs tend to receive more synapses from [[Starburst Amacrine Cell|SAC]] dendrites with the opposite preferred direction, which is evidence for specificity of connections. In principle, a DSGC could indiscriminately receive synapses from all neighboring [[Starburst Amacrine Cell|SAC]] dendrites, which generally encompass a diversity of preferred directions, but this is not the case. The rule of connectivity suggests that a DSGC "inherits" its direction selectivity from its inputs, since [[Starburst Amacrine Cell|SAC]]s make inhibitory (sign-inverting) synapses onto DSGCs.</div></td><td class='diff-marker'> </td><td style="background-color: #f9f9f9; color: #333333; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #e6e6e6; vertical-align: top; white-space: pre-wrap;"><div>From this analysis, the researchers derived a rule governing DSGC-[[Starburst Amacrine Cell|SAC]] connectivity. All [[Starburst Amacrine Cell|SAC]] dendrites and DSGCs respond selectively to ("prefer") motion in some direction. The researchers found that DSGCs tend to receive more synapses from [[Starburst Amacrine Cell|SAC]] dendrites with the opposite preferred direction, which is evidence for specificity of connections. In principle, a DSGC could indiscriminately receive synapses from all neighboring [[Starburst Amacrine Cell|SAC]] dendrites, which generally encompass a diversity of preferred directions, but this is not the case. The rule of connectivity suggests that a DSGC "inherits" its direction selectivity from its inputs, since [[Starburst Amacrine Cell|SAC]]s make inhibitory (sign-inverting) synapses onto DSGCs.</div></td></tr>
</table>Hawaiisunfunhttps://wiki.eyewire.org/index.php?title=E2198/es&diff=12549&oldid=prevHawaiisunfun: Created page with "Los investigadores también reconstruyeron 24 células amacrina estelar (SACs), que se muestran en el Panel c. Estas celdas se dividen en dos cla..."2019-07-20T16:28:37Z<p>Created page with "Los investigadores también reconstruyeron 24 <a href="/index.php?title=C%C3%A9lulas_Amacrina_Estelar&action=edit&redlink=1" class="new" title="Células Amacrina Estelar (page does not exist)">células amacrina estelar</a> (SACs), que se muestran en el Panel c. Estas celdas se dividen en dos cla..."</p>
<table class='diff diff-contentalign-left'>
<col class='diff-marker' />
<col class='diff-content' />
<col class='diff-marker' />
<col class='diff-content' />
<tr style='vertical-align: top;'>
<td colspan='2' style="background-color: white; color:black; text-align: center;">← Older revision</td>
<td colspan='2' style="background-color: white; color:black; text-align: center;">Revision as of 16:28, 20 July 2019</td>
</tr><tr><td colspan="2" class="diff-lineno" id="L15" >Line 15:</td>
<td colspan="2" class="diff-lineno">Line 15:</td></tr>
<tr><td class='diff-marker'> </td><td style="background-color: #f9f9f9; color: #333333; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #e6e6e6; vertical-align: top; white-space: pre-wrap;"><div>Los objetos de color en el panel a son seis DSGC reconstruidos por los investigadores. Los círculos son representaciones de los cuerpos celulares, y las líneas son "esqueletos" de las dendritas. Se dice que cada DSGC está "bistratificado", lo que significa que sus dendritas se ramifican en dos subcapas ("estratos") de la IPL. El número total de estratos en la IPL se estima en alrededor de diez. Una vista de la parte inferior del sándwich (panel b) muestra la ramificación de las dendritas DSGC.</div></td><td class='diff-marker'> </td><td style="background-color: #f9f9f9; color: #333333; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #e6e6e6; vertical-align: top; white-space: pre-wrap;"><div>Los objetos de color en el panel a son seis DSGC reconstruidos por los investigadores. Los círculos son representaciones de los cuerpos celulares, y las líneas son "esqueletos" de las dendritas. Se dice que cada DSGC está "bistratificado", lo que significa que sus dendritas se ramifican en dos subcapas ("estratos") de la IPL. El número total de estratos en la IPL se estima en alrededor de diez. Una vista de la parte inferior del sándwich (panel b) muestra la ramificación de las dendritas DSGC.</div></td></tr>
<tr><td class='diff-marker'> </td><td style="background-color: #f9f9f9; color: #333333; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #e6e6e6; vertical-align: top; white-space: pre-wrap;"></td><td class='diff-marker'> </td><td style="background-color: #f9f9f9; color: #333333; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #e6e6e6; vertical-align: top; white-space: pre-wrap;"></td></tr>
<tr><td class='diff-marker'>−</td><td style="color:black; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div><del class="diffchange diffchange-inline">The researchers also reconstructed </del>24 [[<del class="diffchange diffchange-inline">Starburst Amacrine Cell</del>|<del class="diffchange diffchange-inline">starburst amacrine cell</del>]]<del class="diffchange diffchange-inline">s </del>(SACs), <del class="diffchange diffchange-inline">which are shown in </del>Panel c. <del class="diffchange diffchange-inline">These cells fall in two classes</del>: <del class="diffchange diffchange-inline">ON cells </del>(n=11) <del class="diffchange diffchange-inline">stratifying in one sublayer of the </del>IPL, <del class="diffchange diffchange-inline">and OFF cells </del>(n=13) <del class="diffchange diffchange-inline">stratifying in another sublayer</del>. <del class="diffchange diffchange-inline">Comparison with </del>panel a <del class="diffchange diffchange-inline">shows that </del>[[<del class="diffchange diffchange-inline">Starburst Amacrine Cell</del>|SAC]] <del class="diffchange diffchange-inline">dendrites </del>co-<del class="diffchange diffchange-inline">stratify with </del>DSGC <del class="diffchange diffchange-inline">dendrites</del>, <del class="diffchange diffchange-inline">suggesting that these two cell types could be connected by </del>[[Synapse|<del class="diffchange diffchange-inline">synapses</del>]].</div></td><td class='diff-marker'>+</td><td style="color:black; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div><ins class="diffchange diffchange-inline">Los investigadores también reconstruyeron </ins>24 [[<ins class="diffchange diffchange-inline">Células Amacrina Estelar</ins>|<ins class="diffchange diffchange-inline">células amacrina estelar</ins>]] (SACs), <ins class="diffchange diffchange-inline">que se muestran en el </ins>Panel c. <ins class="diffchange diffchange-inline">Estas celdas se dividen en dos clases</ins>: <ins class="diffchange diffchange-inline">celdas ENCENDIDAS </ins>(n=11) <ins class="diffchange diffchange-inline">que se estratifican en una subcapa de la </ins>IPL, <ins class="diffchange diffchange-inline">y celdas APAGADAS </ins>(n=13) <ins class="diffchange diffchange-inline">que se estratifican en otra subcapa</ins>. <ins class="diffchange diffchange-inline">La comparación con el </ins>panel a <ins class="diffchange diffchange-inline">muestra que </ins>[[<ins class="diffchange diffchange-inline">Células Amacrina Estelar</ins>|SAC]] <ins class="diffchange diffchange-inline">dendritas </ins>co-<ins class="diffchange diffchange-inline">estratifican con dendritas </ins>DSGC, <ins class="diffchange diffchange-inline">lo que sugiere que estos dos tipos de células podrían conectarse mediante </ins>[[Synapse|<ins class="diffchange diffchange-inline">sinapsis</ins>]].</div></td></tr>
<tr><td class='diff-marker'> </td><td style="background-color: #f9f9f9; color: #333333; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #e6e6e6; vertical-align: top; white-space: pre-wrap;"></td><td class='diff-marker'> </td><td style="background-color: #f9f9f9; color: #333333; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #e6e6e6; vertical-align: top; white-space: pre-wrap;"></td></tr>
<tr><td class='diff-marker'> </td><td style="background-color: #f9f9f9; color: #333333; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #e6e6e6; vertical-align: top; white-space: pre-wrap;"><div>As shown in the images below, [[Starburst Amacrine Cell|SAC]] dendrites and DSGC dendrites indeed contact each other. However, not all points of contact are synapses. The researchers conjectured that "varicose" contacts, at which one dendrite seems to grasp or embrace another, were actual synapses, while "incidental" contacts were not synapses.</div></td><td class='diff-marker'> </td><td style="background-color: #f9f9f9; color: #333333; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #e6e6e6; vertical-align: top; white-space: pre-wrap;"><div>As shown in the images below, [[Starburst Amacrine Cell|SAC]] dendrites and DSGC dendrites indeed contact each other. However, not all points of contact are synapses. The researchers conjectured that "varicose" contacts, at which one dendrite seems to grasp or embrace another, were actual synapses, while "incidental" contacts were not synapses.</div></td></tr>
</table>Hawaiisunfunhttps://wiki.eyewire.org/index.php?title=E2198/es&diff=12547&oldid=prevHawaiisunfun: Created page with "Los objetos de color en el panel a son seis DSGC reconstruidos por los investigadores. Los círculos son representaciones de los cuerpos celulares, y las líneas son "esquelet..."2019-07-20T16:25:26Z<p>Created page with "Los objetos de color en el panel a son seis DSGC reconstruidos por los investigadores. Los círculos son representaciones de los cuerpos celulares, y las líneas son "esquelet..."</p>
<table class='diff diff-contentalign-left'>
<col class='diff-marker' />
<col class='diff-content' />
<col class='diff-marker' />
<col class='diff-content' />
<tr style='vertical-align: top;'>
<td colspan='2' style="background-color: white; color:black; text-align: center;">← Older revision</td>
<td colspan='2' style="background-color: white; color:black; text-align: center;">Revision as of 16:25, 20 July 2019</td>
</tr><tr><td colspan="2" class="diff-lineno" id="L13" >Line 13:</td>
<td colspan="2" class="diff-lineno">Line 13:</td></tr>
<tr><td class='diff-marker'> </td><td style="background-color: #f9f9f9; color: #333333; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #e6e6e6; vertical-align: top; white-space: pre-wrap;"><div>En el Panel a de la figura de la derecha, la imagen en escala de grises muestra una sección transversal del volumen SBFSEM que es perpendicular a la retina. Puedes pensar en esto como un corte a través de un sándwich. El relleno es la capa plexiforme interna (IPL), la parte superior del pan, la capa nuclear interna (INL) y la parte inferior del pan, la capa de células ganglionares (GCL). La IPL contiene conexiones sinápticas entre los [[Axon|axones]] de [[Células bipolar|células bipolar]], y la [[Dendrita|dendritas]] de [[Célula amacrina|amacrina]] y [[Célula de ganglio|celulas ganglionares]].</div></td><td class='diff-marker'> </td><td style="background-color: #f9f9f9; color: #333333; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #e6e6e6; vertical-align: top; white-space: pre-wrap;"><div>En el Panel a de la figura de la derecha, la imagen en escala de grises muestra una sección transversal del volumen SBFSEM que es perpendicular a la retina. Puedes pensar en esto como un corte a través de un sándwich. El relleno es la capa plexiforme interna (IPL), la parte superior del pan, la capa nuclear interna (INL) y la parte inferior del pan, la capa de células ganglionares (GCL). La IPL contiene conexiones sinápticas entre los [[Axon|axones]] de [[Células bipolar|células bipolar]], y la [[Dendrita|dendritas]] de [[Célula amacrina|amacrina]] y [[Célula de ganglio|celulas ganglionares]].</div></td></tr>
<tr><td class='diff-marker'> </td><td style="background-color: #f9f9f9; color: #333333; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #e6e6e6; vertical-align: top; white-space: pre-wrap;"></td><td class='diff-marker'> </td><td style="background-color: #f9f9f9; color: #333333; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #e6e6e6; vertical-align: top; white-space: pre-wrap;"></td></tr>
<tr><td class='diff-marker'>−</td><td style="color:black; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div><del class="diffchange diffchange-inline">The colored objects in </del>panel a <del class="diffchange diffchange-inline">are six DSGCs reconstructed by the researchers</del>. <del class="diffchange diffchange-inline">The circles are representations of the cell bodies</del>, <del class="diffchange diffchange-inline">and the lines are </del>"<del class="diffchange diffchange-inline">skeletons</del>" <del class="diffchange diffchange-inline">of the dendrites</del>. <del class="diffchange diffchange-inline">Each </del>DSGC <del class="diffchange diffchange-inline">is said to be </del>"<del class="diffchange diffchange-inline">bistratified,</del>" <del class="diffchange diffchange-inline">which means that its dendrites branch out in two sublayers </del>("<del class="diffchange diffchange-inline">strata</del>") <del class="diffchange diffchange-inline">of the </del>IPL. <del class="diffchange diffchange-inline">The </del>total <del class="diffchange diffchange-inline">number of strata in the </del>IPL <del class="diffchange diffchange-inline">is estimated to be around ten</del>. <del class="diffchange diffchange-inline">A view of the bottom of the sandwich </del>(panel b) <del class="diffchange diffchange-inline">shows the branching of the </del>DSGC <del class="diffchange diffchange-inline">dendrites</del>.</div></td><td class='diff-marker'>+</td><td style="color:black; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div><ins class="diffchange diffchange-inline">Los objetos de color en el </ins>panel a <ins class="diffchange diffchange-inline">son seis DSGC reconstruidos por los investigadores</ins>. <ins class="diffchange diffchange-inline">Los círculos son representaciones de los cuerpos celulares</ins>, <ins class="diffchange diffchange-inline">y las líneas son </ins>"<ins class="diffchange diffchange-inline">esqueletos</ins>" <ins class="diffchange diffchange-inline">de las dendritas</ins>. <ins class="diffchange diffchange-inline">Se dice que cada </ins>DSGC <ins class="diffchange diffchange-inline">está </ins>"<ins class="diffchange diffchange-inline">bistratificado</ins>"<ins class="diffchange diffchange-inline">, lo que significa que sus dendritas se ramifican en dos subcapas </ins>("<ins class="diffchange diffchange-inline">estratos</ins>") <ins class="diffchange diffchange-inline">de la </ins>IPL. <ins class="diffchange diffchange-inline">El número </ins>total <ins class="diffchange diffchange-inline">de estratos en la </ins>IPL <ins class="diffchange diffchange-inline">se estima en alrededor de diez</ins>. <ins class="diffchange diffchange-inline">Una vista de la parte inferior del sándwich </ins>(panel b) <ins class="diffchange diffchange-inline">muestra la ramificación de las dendritas </ins>DSGC.</div></td></tr>
<tr><td class='diff-marker'> </td><td style="background-color: #f9f9f9; color: #333333; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #e6e6e6; vertical-align: top; white-space: pre-wrap;"></td><td class='diff-marker'> </td><td style="background-color: #f9f9f9; color: #333333; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #e6e6e6; vertical-align: top; white-space: pre-wrap;"></td></tr>
<tr><td class='diff-marker'> </td><td style="background-color: #f9f9f9; color: #333333; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #e6e6e6; vertical-align: top; white-space: pre-wrap;"><div>The researchers also reconstructed 24 [[Starburst Amacrine Cell|starburst amacrine cell]]s (SACs), which are shown in Panel c. These cells fall in two classes: ON cells (n=11) stratifying in one sublayer of the IPL, and OFF cells (n=13) stratifying in another sublayer. Comparison with panel a shows that [[Starburst Amacrine Cell|SAC]] dendrites co-stratify with DSGC dendrites, suggesting that these two cell types could be connected by [[Synapse|synapses]].</div></td><td class='diff-marker'> </td><td style="background-color: #f9f9f9; color: #333333; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #e6e6e6; vertical-align: top; white-space: pre-wrap;"><div>The researchers also reconstructed 24 [[Starburst Amacrine Cell|starburst amacrine cell]]s (SACs), which are shown in Panel c. These cells fall in two classes: ON cells (n=11) stratifying in one sublayer of the IPL, and OFF cells (n=13) stratifying in another sublayer. Comparison with panel a shows that [[Starburst Amacrine Cell|SAC]] dendrites co-stratify with DSGC dendrites, suggesting that these two cell types could be connected by [[Synapse|synapses]].</div></td></tr>
</table>Hawaiisunfunhttps://wiki.eyewire.org/index.php?title=E2198/es&diff=12545&oldid=prevHawaiisunfun: Created page with "Ganglio reconstruido y células amacrinas. En el Panel a de la figura de la derecha, la imagen en escala de grises muest..."2019-07-20T16:24:42Z<p>Created page with "<a href="/File:E2198_reconstruction.png" title="File:E2198 reconstruction.png">Ganglio reconstruido y células amacrinas.</a> En el Panel a de la figura de la derecha, la imagen en escala de grises muest..."</p>
<table class='diff diff-contentalign-left'>
<col class='diff-marker' />
<col class='diff-content' />
<col class='diff-marker' />
<col class='diff-content' />
<tr style='vertical-align: top;'>
<td colspan='2' style="background-color: white; color:black; text-align: center;">← Older revision</td>
<td colspan='2' style="background-color: white; color:black; text-align: center;">Revision as of 16:24, 20 July 2019</td>
</tr><tr><td colspan="2" class="diff-lineno" id="L10" >Line 10:</td>
<td colspan="2" class="diff-lineno">Line 10:</td></tr>
<tr><td class='diff-marker'> </td><td style="background-color: #f9f9f9; color: #333333; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #e6e6e6; vertical-align: top; white-space: pre-wrap;"><div>Inmediatamente después de la obtención de imágenes 2P, la retina se fijó, se tiñó y se incrustó en una resina de plástico duro. Se usó una tinción no convencional para marcar los límites entre las neuronas mientras se dejaban sin manchar los orgánulos intracelulares. Se utilizó SBFSEM para obtener imágenes de un volumen de tamaño 350×300×60 µm{{math|<sup>3</sup>}} (izquierda) con resolución de voxel 16.5×16.5×23 nm{{math|<sup>3</sup>}}. Dado que los mismos vasos sanguíneos eran visibles en las imágenes 2P y SBFSEM, los investigadores pudieron encontrar los mismos DSGC en ambas imágenes. Estos están marcados con círculos de colores en la imagen SBFSEM como en la imagen 2P de arriba.</div></td><td class='diff-marker'> </td><td style="background-color: #f9f9f9; color: #333333; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #e6e6e6; vertical-align: top; white-space: pre-wrap;"><div>Inmediatamente después de la obtención de imágenes 2P, la retina se fijó, se tiñó y se incrustó en una resina de plástico duro. Se usó una tinción no convencional para marcar los límites entre las neuronas mientras se dejaban sin manchar los orgánulos intracelulares. Se utilizó SBFSEM para obtener imágenes de un volumen de tamaño 350×300×60 µm{{math|<sup>3</sup>}} (izquierda) con resolución de voxel 16.5×16.5×23 nm{{math|<sup>3</sup>}}. Dado que los mismos vasos sanguíneos eran visibles en las imágenes 2P y SBFSEM, los investigadores pudieron encontrar los mismos DSGC en ambas imágenes. Estos están marcados con círculos de colores en la imagen SBFSEM como en la imagen 2P de arriba.</div></td></tr>
<tr><td class='diff-marker'> </td><td style="background-color: #f9f9f9; color: #333333; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #e6e6e6; vertical-align: top; white-space: pre-wrap;"></td><td class='diff-marker'> </td><td style="background-color: #f9f9f9; color: #333333; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #e6e6e6; vertical-align: top; white-space: pre-wrap;"></td></tr>
<tr><td class='diff-marker'>−</td><td style="color:black; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div>[[Image:e2198_reconstruction.png|thumb|c|right|320px|<del class="diffchange diffchange-inline">Reconstructed ganglion and amacrine cells</del>.]]</div></td><td class='diff-marker'>+</td><td style="color:black; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div>[[Image:e2198_reconstruction.png|thumb|c|right|320px|<ins class="diffchange diffchange-inline">Ganglio reconstruido y células amacrinas</ins>.]]</div></td></tr>
<tr><td class='diff-marker'>−</td><td style="color:black; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div><del class="diffchange diffchange-inline">In </del>Panel a <del class="diffchange diffchange-inline">of the figure on the right</del>, <del class="diffchange diffchange-inline">the gray scale image shows a cross section of the </del>SBFSEM <del class="diffchange diffchange-inline">volume that is </del>perpendicular <del class="diffchange diffchange-inline">to the </del>retina. <del class="diffchange diffchange-inline">You can think of this as </del>a <del class="diffchange diffchange-inline">cut through a sandwich</del>. <del class="diffchange diffchange-inline">The filling is the inner plexiform layer </del>(IPL), <del class="diffchange diffchange-inline">the top piece of bread the inner </del>nuclear <del class="diffchange diffchange-inline">layer </del>(INL) <del class="diffchange diffchange-inline">and the bottom piece of bread the ganglion cell layer </del>(GCL). <del class="diffchange diffchange-inline">The </del>IPL <del class="diffchange diffchange-inline">contains synaptic connections between the </del>[[Axon|<del class="diffchange diffchange-inline">axons</del>]] <del class="diffchange diffchange-inline">of </del>[[<del class="diffchange diffchange-inline">Bipolar Cell</del>|bipolar <del class="diffchange diffchange-inline">cell</del>]]<del class="diffchange diffchange-inline">s</del>, <del class="diffchange diffchange-inline">and the </del>[[<del class="diffchange diffchange-inline">Dendrite</del>|<del class="diffchange diffchange-inline">dendrites</del>]] <del class="diffchange diffchange-inline">of </del>[[<del class="diffchange diffchange-inline">Amacrine Cell</del>|<del class="diffchange diffchange-inline">amacrine</del>]] <del class="diffchange diffchange-inline">and </del>[[<del class="diffchange diffchange-inline">Ganglion Cell</del>|<del class="diffchange diffchange-inline">ganglion cells</del>]].</div></td><td class='diff-marker'>+</td><td style="color:black; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div><ins class="diffchange diffchange-inline">En el </ins>Panel a <ins class="diffchange diffchange-inline">de la figura de la derecha</ins>, <ins class="diffchange diffchange-inline">la imagen en escala de grises muestra una sección transversal del volumen </ins>SBFSEM <ins class="diffchange diffchange-inline">que es </ins>perpendicular <ins class="diffchange diffchange-inline">a la </ins>retina. <ins class="diffchange diffchange-inline">Puedes pensar en esto como un corte </ins>a <ins class="diffchange diffchange-inline">través de un sándwich</ins>. <ins class="diffchange diffchange-inline">El relleno es la capa plexiforme interna </ins>(IPL), <ins class="diffchange diffchange-inline">la parte superior del pan, la capa </ins>nuclear <ins class="diffchange diffchange-inline">interna </ins>(INL) <ins class="diffchange diffchange-inline">y la parte inferior del pan, la capa de células ganglionares </ins>(GCL). <ins class="diffchange diffchange-inline">La </ins>IPL <ins class="diffchange diffchange-inline">contiene conexiones sinápticas entre los </ins>[[Axon|<ins class="diffchange diffchange-inline">axones</ins>]] <ins class="diffchange diffchange-inline">de </ins>[[<ins class="diffchange diffchange-inline">Células bipolar</ins>|<ins class="diffchange diffchange-inline">células </ins>bipolar]], <ins class="diffchange diffchange-inline">y la </ins>[[<ins class="diffchange diffchange-inline">Dendrita</ins>|<ins class="diffchange diffchange-inline">dendritas</ins>]] <ins class="diffchange diffchange-inline">de </ins>[[<ins class="diffchange diffchange-inline">Célula amacrina</ins>|<ins class="diffchange diffchange-inline">amacrina</ins>]] <ins class="diffchange diffchange-inline">y </ins>[[<ins class="diffchange diffchange-inline">Célula de ganglio</ins>|<ins class="diffchange diffchange-inline">celulas ganglionares</ins>]].</div></td></tr>
<tr><td class='diff-marker'> </td><td style="background-color: #f9f9f9; color: #333333; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #e6e6e6; vertical-align: top; white-space: pre-wrap;"></td><td class='diff-marker'> </td><td style="background-color: #f9f9f9; color: #333333; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #e6e6e6; vertical-align: top; white-space: pre-wrap;"></td></tr>
<tr><td class='diff-marker'> </td><td style="background-color: #f9f9f9; color: #333333; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #e6e6e6; vertical-align: top; white-space: pre-wrap;"><div>The colored objects in panel a are six DSGCs reconstructed by the researchers. The circles are representations of the cell bodies, and the lines are "skeletons" of the dendrites. Each DSGC is said to be "bistratified," which means that its dendrites branch out in two sublayers ("strata") of the IPL. The total number of strata in the IPL is estimated to be around ten. A view of the bottom of the sandwich (panel b) shows the branching of the DSGC dendrites.</div></td><td class='diff-marker'> </td><td style="background-color: #f9f9f9; color: #333333; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #e6e6e6; vertical-align: top; white-space: pre-wrap;"><div>The colored objects in panel a are six DSGCs reconstructed by the researchers. The circles are representations of the cell bodies, and the lines are "skeletons" of the dendrites. Each DSGC is said to be "bistratified," which means that its dendrites branch out in two sublayers ("strata") of the IPL. The total number of strata in the IPL is estimated to be around ten. A view of the bottom of the sandwich (panel b) shows the branching of the DSGC dendrites.</div></td></tr>
</table>Hawaiisunfun