DRD4-RGC

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DRD4-DSGCs are On-Off direction selective ganglion cells that respond to global posterior motion (backward motion in relation to the world). These cells were discovered in transgenic mice that express GFP under the control of the dopamine receptor 4 promoter (DRD4-EGFP). Interestingly, the GFP positive RGCs in this mouse line all have characteristics of On-Off DSGCs, and exclusively prefer posterior motion.

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