Autapse

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An autapse seen in the 3D view of EyeWire

An autapse is a synapse that a neuron forms with itself. In EyeWire's 2D view, these generally appear to be branches that move away from the main branch, approach it again, but only touch again along a cell membrane. They have been hypothesized to serve as short-term analog memory storage.[1]

History

Autapses have been known since at least 1972.[2]

References

  1. Seung, SH; Lee, DD; Reis, BY; Tank, DW (2000). "The Autapse: A Simple Illustration of Short-Term Analog Memory Storage by Tuned Synaptic Feedback", J. Computational Neuroscience 9:171-185. doi: 10.1023/A:1008971908649.
  2. Van der Loos, H; Glaser EM (1972). "Autapses in neocortex cerebri: synapses between a pyramidal cell's axon and its own dendrites", Brain Research 48:355-60. doi: 10.1016/0006-8993(72)90189-8. Paywalled.