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Message definition (Amacrine Cell )
===Open questions===
===Open questions===
Though it is more or less well-established how inhibitory amacrine cells function, it is less clear what functions non-GABAergic/glycinergic amacrine cells have in the retina. In particular, it is not well understood for which functions [[Starburst Amacrine Cell|starburst amacrine cells]] require acetylcholine secretion or how [[Starburst Amacrine Cell|starburst amacrine cells]] might use both GABA and acetylcholine in concert to accomplish certain fucntions. [[Starburst Amacrine Cell|Starburst amacrine cells]] also exhibit very curious biophysics in that any given individual SAC dendrite is selectively activated by visual stimuli centrifugal with respect to that particular dendrite.<ref name="Denk 2002">Thomas Euler, Peter B. Detwiler & Winfried Denk (2002). [http://retina.anatomy.upenn.edu/pdfiles/5908.pdf Directionally selective calcium signals in dendrites of starburst amacrine cells] Nature <strong>418</strong>: 845-852</ref> The mechanism for this selectivity remains unknown. Translation ===Open questions=== Open questions
Though it is more or less well-established how inhibitory amacrine cells function, it is less clear what functions non-GABAergic/glycinergic amacrine cells have in the retina. In particular, it is not well understood for which functions
starburst amacrine cells require acetylcholine secretion or how
starburst amacrine cells might use both GABA and acetylcholine in concert to accomplish certain fucntions.
Starburst amacrine cells also exhibit very curious biophysics in that any given individual SAC dendrite is selectively activated by visual stimuli centrifugal with respect to that particular dendrite.
[1] The mechanism for this selectivity remains unknown.
↑ Thomas Euler, Peter B. Detwiler & Winfried Denk (2002). Directionally selective calcium signals in dendrites of starburst amacrine cells Nature 418 : 845-852
