Translations:Bipolar Cell/24/en

In EyeWire, the primary focus is to catalog the connections made between ganglion, bipolar, and amacrine cells. Understanding these synaptic inputs will allow a better comprehension of how retinal processing is able to create emergent ganglion cell functions, such as direction-selective cells, motion-selective cells, and even general center-surround inhibition circuits. Is it hypothesized that these properties do not only arise once the signals reach the ganglion cells, but rather begin to form within the upstream signals exchanged within the outer plexiform layer (OPL) where the bipolar cells synapse with horizontal cells and photoreceptors. Compiling information on the bipolar cells connected to a given direction-selective ganglion cells may give a clearer picture of how these computations are developed and transmitted.