Translations:Amacrine Cell/7/en

Amacrine cells are responsible for mediating "antagonistic inputs from bipolar cells in [a] ganglion cell's surround." Thus, amacrine cells take excitatory signals coming from bipolar cells and consequently mediate inhibitory signals to a postsynaptic ganglion cell in the 'center' of its respective receptive field. In terms of visual response properties, this means that an amacrine cell in this sort of lateral pathway located within the surround of an ON-center ganglion cell's receptive field will depolarize in the presence of light on the surround of the ganglion cell's receptive field, while one located in the surround of an OFF-center ganglion cell's receptive field will hyperpolarize under the same circumstances (and depolarize in the absence of light on the surround). ON-center ganglion cells are therefore inhibited by amacrine cells in their surrounds when light shines on the surround of their receptive fields, while OFF-center ganglion cells do not receive this inhibitory input under the same circumstances, but instead receive it in the absence of light on the ganglion cell receptive field surround.