Difference between revisions of "BC2"
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− | '''Bipolar Cell Type 2 (BC2)''' are one of five OFF bipolar cells in the retina. They stratify in the OFF sublamina in the inner plexiform layer (IPL) | + | '''Bipolar Cell Type 2 (BC2)''' are one of five OFF bipolar cells in the retina. They stratify in the OFF sublamina in the inner plexiform layer (IPL) |
==Molecular Definition== | ==Molecular Definition== | ||
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+ | There are several markers that have been used to label BC2s, although not all of them are selective. | ||
[[File:Cb2gfp_huberman2008.PNG|thumb|right|400px|GFP positive cells in whole mount CB2-GFP mouse retina. A. whole mount retina. Scale = 500um B. GFP positive cells. C. Alpha RGCs are immunpositive to SMI-32 cells. D. GFP positive cells are all SMI-32 positive. CB2-RGCs appear to be alpha type RGCs. scale = 125um. E. GFP positive cells in the GCL (CB2-RGCs) and INL (amacrine cells). Scale = 100um. Image adapted from Huberman et al., 2008]] | [[File:Cb2gfp_huberman2008.PNG|thumb|right|400px|GFP positive cells in whole mount CB2-GFP mouse retina. A. whole mount retina. Scale = 500um B. GFP positive cells. C. Alpha RGCs are immunpositive to SMI-32 cells. D. GFP positive cells are all SMI-32 positive. CB2-RGCs appear to be alpha type RGCs. scale = 125um. E. GFP positive cells in the GCL (CB2-RGCs) and INL (amacrine cells). Scale = 100um. Image adapted from Huberman et al., 2008]] |
Revision as of 17:32, 28 September 2015
Bipolar Cell Type 2 (BC2) are one of five OFF bipolar cells in the retina. They stratify in the OFF sublamina in the inner plexiform layer (IPL)
Contents
Molecular Definition
There are several markers that have been used to label BC2s, although not all of them are selective.
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Physiology
[[File:Cb2physio_huberman2008.PNG|thumb|500px|none|Physiological responses of CB2-RGCs to visual stimuli. A. Membrane potential response shows spike at offset of flash. B. Average subthreshold flash response of seven cells (gray), and average flash response of two example cells (blue, red). Image adapted from Huberman et al., 2
Anatomy
Dendritic Morphology
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Retinal Input
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Central Projections
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Development
History
References
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